Ensuring timely antibody delivery in the face of supply chain challenges - contact us for solutions

Mouse Anti-Mouse Bax-UNLB (5B7)

Cat. No.:
10050-01
Purified Anti-Mouse Bax antibody for use in flow cytometry, immunocytochemistry, western blot, immunoprecipitation, and purification assays.
$198.00
Size Price (USD) Quantity
0.1 mg $198.00
More Information
Clone 5B7
Isotype Mouse IgG1κ
Isotype Control Mouse IgG1-UNLB (15H6)
Specificity Mouse Bax
Alternative Names Apoptosis regulator BAX, BCL2 associated X protein
Description Bax is a 20-22 kDa member of the Bcl-2 family of proteins involved in regulation of programmed cell death, or apoptosis. In murine thymocytes it is expressed primarily as a cytoplasmic protein. Over-expression of Bax promotes apoptosis by formation of homodimers and through heterodimerization with Bcl-2, an inhibitor of apoptosis. The monoclonal antibody 5B7 recognizes both native and activated forms of Bax as well as Bax-Bcl-2 and Bax-Bcl-xL heterodimers.
Immunogen Murine Bax peptide (a.a. 3-16)
Conjugate UNLB (Unconjugated)
Buffer Formulation Borate buffered saline, pH 8.2
Clonality Monoclonal
Concentration 0.1 mg/mL
Volume 1.0 mL
Recommended Storage 2-8°C
Applications Western Blot – Quality tested 1-3,5
Immunoprecipitation – Reported in literature 1,3,5
Flow Cytometry – Reported in literature 4
Immunocytochemistry – Reported in literature 4
Purification – Reported in literature 5

RRID Number AB_2794106
Gene ID 12028 (Mouse)
Gene ID Symbol Bax (Mouse)
UniProt ID Q07813 (Mouse)
UniProt Name BAX_MOUSE (Mouse)

Certificate of Analysis Lookup

Enter the Catalog Number and Lot Number for the Certificate of Analysis you wish to view


Need help with this product?
or call 800.722.2255
  1. 1. Hsu Y, Youle RJ. Nonionic detergents induce dimerization among members of the Bcl-2 family. J Biol Chem. 1997;272:13829-34. (Immunogen, WB, IP)
  2. 2. Hsu Y, Wolter KG, Youle RJ. Cytosol-to-membrane redistribution of Bax and Bcl-XL during apoptosis. Proc Natl Acad Sci USA. 1997;94:3668-72. (WB)
  3. 3. Havasi A, Li Z, Wang Z, Martin JL, Botla V, Ruchalski K, et al. Hsp27 inhibits Bax activation and apoptosis via a phosphatidylinositol 3-kinase-dependent mechanism. J Biol Chem. 2008;283:12305-13. (WB, IP)
  4. 4. Halicka HD, Smolewski P, Darzynkiewicz Z, Dai W, Traganos F. Arsenic trioxide arrests cells early in mitosis leading to apoptosis. Cell Cycle. 2002;1:200-8. (FC, ICC)
  5. 5. Hsu Y, Youle RJ. Bax in murine thymus is a soluble monomeric protein that displays differential detergent-induced conformations. J Biol Chem. 1998;273:10777-83. (WB, IP, Purification)
See All References