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Rat Anti-Mouse TNF-α
ANTIGEN DESCRIPTION
The monoclonal antibodies MP6-XT3 and MP6-XT22 are specific for mouse tumor necrosis factor-α (TNF-α), a 17 kDa cytokine that is secreted by numerous cells including activated monocytes and macrophages as well as B cells, T cells and fibroblasts. TNF-α has been shown to have pro-inflammatory properties including the induction of fever and the production of collagenase by synovial cells. It also perpetuates the inflammatory response through a cascade of cytokines, including IL-1 and IL-6 which have overlapping properties.
[Technical Bulletin / References ]
Back to Pro-Inflammatory Research - Specificity Mouse
Cat. No.
Product Description
Clone
Size
USD Price
Order Qty
10229-01
Rat Anti-Mouse TNF-a-UNLB
MP6-XT3
0.5 mg
$200.00
10229-08
Rat Anti-Mouse TNF-a-BIOT
MP6-XT3
0.5 mg
$230.00
10229-14
Rat Anti-Mouse TNF-a-LE/AF
MP6-XT3
0.5 mg
$280.00
FORMAT ABBREVIATIONS:
UNLB
- purified, unlabeled antibody
FITC
- fluorescein isothiocyanate-labeled
TRITC
- tetramethlyrhodamine isothiocyanate
AP
- alkaline phosphatase-labeled
HRP
- horseradish peroxidase-labeled
BGAL
- B-galactosidase-labeled
TXRD
- Texas Red
TM
BIOT
- biotin-labeled
R-PE
- R-phycoerythrin-labeled
R-PE/TXRD
- R-phycoerythrin/Texas Red
TM
APC
- allophycocyanin
CY3
- Cyanine
TM
3-labeled *
SPRD
- SpectralRed
TM
-labeled *
LE/AF
- low endotoxin/azide-free
CY5
- Cyanine
TM
5-labeled *
R-PE/CY5.5
- R-phycoerythrin/Cyanine
TM
5.5-labeled *
R-PE/CY7
- R-phycoerythrin/Cyanine
TM
7-labeled *
APC/CY5.5
- allophycocyanin/Cyanine
TM
5.5-labeled *
APC/CY7
- allophycocyanin/Cyanine
TM
7-labeled *
FLMA
- fluorescein-5-malemide-labeled
SEPH
- sepharose-labeled
BIMA
- biotin-maleimide-labeled
NOTE:
*SpectralRed
TM
(SPRD) is a tandem conjugate of R-phycoerythrin and CY
TM
5. It was developed as a reagent for 3-color flow cytometry on instruments with only 488 nm excitation source. It requires minimal (0-2%) FL2/FL3 compensation.
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