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Rat Anti-Mouse Interleukin-17 (IL-17) ELISA Set

BACKGROUND
Interleukin 17 (IL-17) is a 30kD homodimeric glycoprotein that is secreted by a variety of cells including activated CD4+ and CD8+ T cells, natural killer cells and granulocytes[1]. This proinflammatory cytokine signals through the IL-17 receptor which is expressed in multiple tissues. IL-17 is a pleiotropic cytokine and can induce release of several pro-inflammatory cytokines including IL-1β, IL-6 and tumor necrosis factor alpha and chemokines such as IL-8[2-4]. Furthermore, it can stimulate release of inducible nitric oxide synthase and cyclooxygenase 2 and promote stem cell factor- and granulocyte-colony stimulating factor-mediated granulopoiesis[5,6]. In agreement with its pro-inflammatory properties, a number of studies have linked over-expression of IL-17 to several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis[7,8].
[Technical Bulletin / References ] Back to Pro-Inflammatory Research - Elisa Set
 Cat. No.Product DescriptionCloneSize
USD Price
Order Qty
14500-01
 
Anti-Mouse IL-17 Elisa Set
Set
$350.00
FORMAT ABBREVIATIONS:
UNLB - purified, unlabeled antibody
FITC - fluorescein isothiocyanate-labeled
TRITC - tetramethlyrhodamine isothiocyanate
AP - alkaline phosphatase-labeled
HRP - horseradish peroxidase-labeled
BGAL - B-galactosidase-labeled
TXRD - Texas RedTM
BIOT - biotin-labeled
R-PE - R-phycoerythrin-labeled
R-PE/TXRD - R-phycoerythrin/Texas RedTM
APC - allophycocyanin
 CY3 - CyanineTM 3-labeled *
SPRD - SpectralRedTM-labeled *
LE/AF - low endotoxin/azide-free
CY5 - CyanineTM5-labeled *
R-PE/CY5.5 - R-phycoerythrin/CyanineTM5.5-labeled *
R-PE/CY7 - R-phycoerythrin/CyanineTM7-labeled *
APC/CY5.5 - allophycocyanin/CyanineTM5.5-labeled *
APC/CY7 - allophycocyanin/CyanineTM7-labeled *
FLMA - fluorescein-5-malemide-labeled
SEPH - sepharose-labeled
BIMA - biotin-maleimide-labeled
NOTE: *SpectralRedTM (SPRD) is a tandem conjugate of R-phycoerythrin and CYTM5. It was developed as a reagent for 3-color flow cytometry on instruments with only 488 nm excitation source. It requires minimal (0-2%) FL2/FL3 compensation.