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Hamster Anti-Mouse CD3ε

ANTIGEN DESCRIPTION
CD3ε, a member of the immunoglobulin superfamily of cell surface receptors, is comprised of five invariable chains ranging in size from 16-28 kDa and is closely associated with the T cell antigen receptor (TCR). It is expressed on all T cells of all mouse strains. CD3 plays a major role in signaling during antigen recognition, leading to T-cell activation. The 145-2C11 monoclonal antibody recognizes an epitope on the 25kD ε chain of the CD3/TCR complex. In the presence of Fc receptor-bearing accessory cells, soluble 145-2C11 can activate primed and naïve T cell in vitro. 145-2C11 can also induce redirected lysis of specific target cells by CTL clones and it can block lysis of specific target cells by antigen-specific CTL’s. Immobilized 145-2C11 can activate both normal T lymphocytes and cloned T cell lines. Under certain conditions, T cell activation by 145-2C11 may result in apoptotic cell death. [1-6]
[Technical Bulletin / References ] Back to CD Markers and Other Cell Surface Proteins - Specificity Mouse
 Cat. No.Product DescriptionCloneSize
USD Price
Order Qty
1530-01
 
Hamster Anti-Mouse CD3e-UNLB
145-2C11 0.5 mg
$158.00
1530-02
 
Hamster Anti-Mouse CD3e-FITC
145-2C11 0.5 mg
$225.00
1530-02S
 
Hamster Anti-Mouse CD3e-FITC
145-2C11 0.1 mg
$80.00
1530-09
 
Hamster Anti-Mouse CD3e-R-PE
145-2C11 0.1 mg
$100.00
1530-09L
 
Hamster Anti-Mouse CD3e-R-PE
145-2C11 0.2 mg
$158.00
1530-11
 
Hamster Anti-Mouse CD3e-APC
145-2C11 0.1 mg
$222.00
1530-13
 
Hamster Anti-Mouse CD3e-SPRD
145-2C11 0.1 mg
$177.00
1530-14
 
Hamster Anti-Mouse CD3e-LE/AF
145-2C11 0.5 mg
$198.00
1530-28
 
Hamster Anti-Mouse CD3e-BIMA
145-2C11 0.5mg
$208.00
1530-30
 
Hamster Anti-Mouse CD3e-Alexa Fluor 488
145-2C11 0.1 mg
$190.00
1530-31
 
Hamster Anti-Mouse CD3e-Alexa Fluor 647
145-2C11 0.1 mg
$190.00
FORMAT ABBREVIATIONS:
UNLB - purified, unlabeled antibody
FITC - fluorescein isothiocyanate-labeled
TRITC - tetramethlyrhodamine isothiocyanate
AP - alkaline phosphatase-labeled
HRP - horseradish peroxidase-labeled
BGAL - B-galactosidase-labeled
TXRD - Texas RedTM
BIOT - biotin-labeled
R-PE - R-phycoerythrin-labeled
R-PE/TXRD - R-phycoerythrin/Texas RedTM
APC - allophycocyanin
 CY3 - CyanineTM 3-labeled *
SPRD - SpectralRedTM-labeled *
LE/AF - low endotoxin/azide-free
CY5 - CyanineTM5-labeled *
R-PE/CY5.5 - R-phycoerythrin/CyanineTM5.5-labeled *
R-PE/CY7 - R-phycoerythrin/CyanineTM7-labeled *
APC/CY5.5 - allophycocyanin/CyanineTM5.5-labeled *
APC/CY7 - allophycocyanin/CyanineTM7-labeled *
FLMA - fluorescein-5-malemide-labeled
SEPH - sepharose-labeled
BIMA - biotin-maleimide-labeled
NOTE: *SpectralRedTM (SPRD) is a tandem conjugate of R-phycoerythrin and CYTM5. It was developed as a reagent for 3-color flow cytometry on instruments with only 488 nm excitation source. It requires minimal (0-2%) FL2/FL3 compensation.