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Rat Anti-Mouse CD23 (FcεRII)

ANTIGEN DESCRIPTION
The CD23 antigen is the low affinity IgE Fc receptor, which is a 49 kDa protein with 38 and 28 kDa fragments.[1] It is expressed on most mature, conventional B cells (but not on peritoneal CD5+ B cells), and can also be found on the surface of T cells, macrophages and platelets.[1-6] It is distinct from the high affinity IgE receptors found on basophils and mast cells, which mediate allergic reactions. The low affinity receptors are thought to play a role in isotype specific immunoregulation.[3] The regulation of CD23 surface expression appears to be integral with the complex IgE system, which involves interactions of cells, cytokines, antibodies and regulatory factors.[2-6] CD23 has been described as a “membrane bound cytokine," in that the soluble cleavage products of CD23 are themselves able to act as cytokines in vitro.[6]
[Technical Bulletin / References ] Back to CD Markers and Other Cell Surface Proteins - Specificity Mouse
 Cat. No.Product DescriptionCloneSize
USD Price
Order Qty
1585-01
 
Rat Anti-Mouse CD23/FCeRII-UNLB
2G8 0.5 mg
$218.00
1585-02
 
Rat Anti-Mouse CD23/FCeRII-FITC
2G8 0.5 mg
$245.00
1585-08
 
Rat Anti-Mouse CD23/FCeRII-BIOT
2G8 0.5 mg
$225.00
1585-09
 
Rat Anti-Mouse CD23/FCeRII-R-PE
2G8 0.1 mg
$180.00
1585-09L
 
Rat Anti-Mouse CD23/FCeRII-R-PE
2G8 0.2 mg
$245.00
1585-11
 
Rat Anti-Mouse CD23/FceRII-APC
2G8 0.1 mg
$215.00
1585-14
 
Rat Anti-Mouse CD23/FCeRII-LE/AF
2G8 0.5 mg
$320.00
1585-17
 
Rat Anti-Mouse CD23/FCeRII-PE/CY7
2G8 0.1 mg
$192.00
FORMAT ABBREVIATIONS:
UNLB - purified, unlabeled antibody
FITC - fluorescein isothiocyanate-labeled
TRITC - tetramethlyrhodamine isothiocyanate
AP - alkaline phosphatase-labeled
HRP - horseradish peroxidase-labeled
BGAL - B-galactosidase-labeled
TXRD - Texas RedTM
BIOT - biotin-labeled
R-PE - R-phycoerythrin-labeled
R-PE/TXRD - R-phycoerythrin/Texas RedTM
APC - allophycocyanin
 CY3 - CyanineTM 3-labeled *
SPRD - SpectralRedTM-labeled *
LE/AF - low endotoxin/azide-free
CY5 - CyanineTM5-labeled *
R-PE/CY5.5 - R-phycoerythrin/CyanineTM5.5-labeled *
R-PE/CY7 - R-phycoerythrin/CyanineTM7-labeled *
APC/CY5.5 - allophycocyanin/CyanineTM5.5-labeled *
APC/CY7 - allophycocyanin/CyanineTM7-labeled *
FLMA - fluorescein-5-malemide-labeled
SEPH - sepharose-labeled
BIMA - biotin-maleimide-labeled
NOTE: *SpectralRedTM (SPRD) is a tandem conjugate of R-phycoerythrin and CYTM5. It was developed as a reagent for 3-color flow cytometry on instruments with only 488 nm excitation source. It requires minimal (0-2%) FL2/FL3 compensation.