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Rat Anti-Mouse CD16/32 (fcγR)

ANTIGEN DESCRIPTION
The lymphocyte Fcγ receptors recognize the Fc portion of IgG, presented either as immune complexes or as free antibody. The different classes of receptors are distinct because of varying size, tissue distribution and affinity for IgGs. The Fc type II receptor is expressed on a wide variety of cells including B cells, hematopoietic cells, monocyte/macrophages, neutrophils, platelets, Langerhans cells, eosinophils, basophils, trophoblasts, and endothelial cells of the placenta.[1,2] The Fcγ type III receptors are higher affinity than the type II and are expressed on macrophages, NK cells and neutrophils. Both types of receptors can be expressed on the same cell and in varying ratios.[1] The receptors are constitutively expressed, although cytokines and lymphokines can modulate their expression.[4] Besides identifying FcγR+ cells, monoclonal antibodies to the FcγII/III receptor have been used to block Fc receptor binding of IgG, Fcmediated signal transduction and effector functions, clearance of immune complexes and to attenuate infection by organisms dependent on FcγR for parasitic invasion.[4-6] The monoclonal antibody 93 recognizes a conformational epitope formed by FcγII and FcγIII receptors.
[Technical Bulletin / References ] Back to CD Markers and Other Cell Surface Proteins - Specificity Mouse
 Cat. No.Product DescriptionCloneSize
USD Price
Order Qty
1630-01
 
Rat Anti-Mouse CD16/32-UNLB
93 0.5 mg
$192.00
1630-02
 
Rat Anti-Mouse CD16/32-FITC
93 0.5 mg
$235.00
1630-08
 
Rat Anti-Mouse CD16/32-BIOT
93 0.5 mg
$255.00
1630-09
 
Rat Anti-Mouse CD16/32-R-PE
93 0.1 mg
$155.00
1630-09L
 
Rat Anti-Mouse CD16/32-R-PE
93 0.2 mg
$245.00
1630-11
 
Rat Anti-Mouse CD16/32-APC
93 0.1 mg
$255.00
1630-13
 
Rat Anti-Mouse CD16/32-SPRD
93 0.1 mg
$265.00
1630-14
 
Rat Anti-Mouse CD16/32-LE/AF
93 0.5 mg
$245.00
1630-16
 
Rat Anti-Mouse CD16/32-PE/CY5.5
93 0.1 mg
$195.00
1630-17
 
Rat Anti-Mouse CD16/32-PE/CY7
93 0.1 mg
$187.00
FORMAT ABBREVIATIONS:
UNLB - purified, unlabeled antibody
FITC - fluorescein isothiocyanate-labeled
TRITC - tetramethlyrhodamine isothiocyanate
AP - alkaline phosphatase-labeled
HRP - horseradish peroxidase-labeled
BGAL - B-galactosidase-labeled
TXRD - Texas RedTM
BIOT - biotin-labeled
R-PE - R-phycoerythrin-labeled
R-PE/TXRD - R-phycoerythrin/Texas RedTM
APC - allophycocyanin
 CY3 - CyanineTM 3-labeled *
SPRD - SpectralRedTM-labeled *
LE/AF - low endotoxin/azide-free
CY5 - CyanineTM5-labeled *
R-PE/CY5.5 - R-phycoerythrin/CyanineTM5.5-labeled *
R-PE/CY7 - R-phycoerythrin/CyanineTM7-labeled *
APC/CY5.5 - allophycocyanin/CyanineTM5.5-labeled *
APC/CY7 - allophycocyanin/CyanineTM7-labeled *
FLMA - fluorescein-5-malemide-labeled
SEPH - sepharose-labeled
BIMA - biotin-maleimide-labeled
NOTE: *SpectralRedTM (SPRD) is a tandem conjugate of R-phycoerythrin and CYTM5. It was developed as a reagent for 3-color flow cytometry on instruments with only 488 nm excitation source. It requires minimal (0-2%) FL2/FL3 compensation.