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Rat Anti-Mouse CD86 (B7-2)

ANTIGEN DESCRIPTION
CD86, also known as B7-2, is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is expressed at high levels on resting peripheral monocytes and dendritic cells and at very low density on resting B and T lymphocytes.[1-5] CD86 expression is rapidly upregulated by B-cell specific stimuli with peak expression at 18-42 hours after stimulation.[1,5] CD86, along with CD80/B7-1, is an important accessory molecule in T cell costimulation via its interaction with CD28 and CD152/CTLA-4. Since CD86 has rapid kinetics of induction, it is believed to be the major CD28 ligand expressed early in the immune response.[1-9] The monoclonal antibody GL1 blocks mixed lymphocyte reactions and stimulation of T cells by antigen-presenting cells.[1,3,5]
[Technical Bulletin / References ] Back to CD Markers and Other Cell Surface Proteins - Specificity Mouse
 Cat. No.Product DescriptionCloneSize
USD Price
Order Qty
1735-01
 
Rat Anti-Mouse CD86/B7-2-UNLB
GL1 0.5 mg
$192.00
1735-02
 
Rat Anti-Mouse CD86/B7-2-FITC
GL1 0.5 mg
$230.00
1735-08
 
Rat Anti-Mouse CD86/B7-2-BIOT
GL1 0.5 mg
$222.00
1735-09
 
Rat Anti-Mouse CD86/B7-2-R-PE
GL1 0.1 mg
$185.00
1735-09L
 
Rat Anti-Mouse CD86/B7-2-R-PE
GL1 0.2 mg
$245.00
1735-11
 
Rat Anti-Mouse CD86/B7-2-APC
GL1 0.1 mg
$235.00
1735-13
 
Rat Anti-Mouse CD86/B7-2-SPRD
GL1 0.1 mg
$235.00
1735-14
 
Rat Anti-Mouse CD86/B7-2-LE/AF
GL1 0.5 mg
$245.00
1735-17
 
Rat Anti-Mouse CD86/B7-2-PE/CY7
GL1 0.1 mg
$235.00
FORMAT ABBREVIATIONS:
UNLB - purified, unlabeled antibody
FITC - fluorescein isothiocyanate-labeled
TRITC - tetramethlyrhodamine isothiocyanate
AP - alkaline phosphatase-labeled
HRP - horseradish peroxidase-labeled
BGAL - B-galactosidase-labeled
TXRD - Texas RedTM
BIOT - biotin-labeled
R-PE - R-phycoerythrin-labeled
R-PE/TXRD - R-phycoerythrin/Texas RedTM
APC - allophycocyanin
 CY3 - CyanineTM 3-labeled *
SPRD - SpectralRedTM-labeled *
LE/AF - low endotoxin/azide-free
CY5 - CyanineTM5-labeled *
R-PE/CY5.5 - R-phycoerythrin/CyanineTM5.5-labeled *
R-PE/CY7 - R-phycoerythrin/CyanineTM7-labeled *
APC/CY5.5 - allophycocyanin/CyanineTM5.5-labeled *
APC/CY7 - allophycocyanin/CyanineTM7-labeled *
FLMA - fluorescein-5-malemide-labeled
SEPH - sepharose-labeled
BIMA - biotin-maleimide-labeled
NOTE: *SpectralRedTM (SPRD) is a tandem conjugate of R-phycoerythrin and CYTM5. It was developed as a reagent for 3-color flow cytometry on instruments with only 488 nm excitation source. It requires minimal (0-2%) FL2/FL3 compensation.