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Rat Anti-Mouse CD24 (HSA)

ANTIGEN DESCRIPTION
CD24 is expressed in B cells until their terminal differentiation into plasma cells.[1] It has been used widely as a marker to fractionate different B-lineage differentiation stages.[10] CD24 has been found on a variety of other hematopoietic and neural cell types, and is now classified as a costimulatory molecule.[2-4] The CD24/HSA molecule is composed mostly of carbohydrate, with a protein core of only 31-35 amino acids in the human and 27 amino acids in the mouse.[1,3] The molecular mass is variable, ranging from 38-70 kDa.[3] CD24 is now included in the large group of phosphatidylinositol-anchored membrane proteins.[1-4] Studies with purified CD24 applied to latex beads have demonstrated a self-binding property, suggesting that the molecule is capable of promoting homotypic aggregation, binding and cell adhesion.[3] This is supported by earlier observations of the blockade of B cell lymphoblast aggregation with anti-CD24 monoclonal antibody.[6] Recent studies of murine CD24 have assigned a role for CD24/HSA as a ligand for P-selectin, a calcium-dependent lectin.[7]
[Technical Bulletin / References ] Back to CD Markers and Other Cell Surface Proteins - Specificity Mouse
 Cat. No.Product DescriptionCloneSize
USD Price
Order Qty
1815-01
 
Rat Anti-Mouse CD24/HSA-UNLB
30-F1 0.5 mg
$225.00
1815-02
 
Rat Anti-Mouse CD24/HSA-FITC
30-F1 0.5 mg
$265.00
1815-02S
 
Rat Anti-Mouse CD24/HSA-FITC
30-F1 0.1 mg
$115.00
1815-08
 
Rat Anti-Mouse CD24/HSA-BIOT
30-F1 0.5 mg
$285.00
1815-09
 
Rat Anti-Mouse CD24/HSA-R-PE
30-F1 0.1 mg
$120.00
1815-09L
 
Rat Anti-Mouse CD24/HSA-R-PE
30-F1 0.2 mg
$198.00
1815-11
 
Rat Anti-Mouse CD24/HAS-APC
30-F1 0.1 mg
$220.00
1815-13
 
Rat Anti-Mouse CD24/HSA-SPRD
30-F1 0.1 mg
$260.00
1815-14
 
Rat Anti-Mouse CD24/HSA-LE/AF
30-F1 0.5 mg
$300.00
FORMAT ABBREVIATIONS:
UNLB - purified, unlabeled antibody
FITC - fluorescein isothiocyanate-labeled
TRITC - tetramethlyrhodamine isothiocyanate
AP - alkaline phosphatase-labeled
HRP - horseradish peroxidase-labeled
BGAL - B-galactosidase-labeled
TXRD - Texas RedTM
BIOT - biotin-labeled
R-PE - R-phycoerythrin-labeled
R-PE/TXRD - R-phycoerythrin/Texas RedTM
APC - allophycocyanin
 CY3 - CyanineTM 3-labeled *
SPRD - SpectralRedTM-labeled *
LE/AF - low endotoxin/azide-free
CY5 - CyanineTM5-labeled *
R-PE/CY5.5 - R-phycoerythrin/CyanineTM5.5-labeled *
R-PE/CY7 - R-phycoerythrin/CyanineTM7-labeled *
APC/CY5.5 - allophycocyanin/CyanineTM5.5-labeled *
APC/CY7 - allophycocyanin/CyanineTM7-labeled *
FLMA - fluorescein-5-malemide-labeled
SEPH - sepharose-labeled
BIMA - biotin-maleimide-labeled
NOTE: *SpectralRedTM (SPRD) is a tandem conjugate of R-phycoerythrin and CYTM5. It was developed as a reagent for 3-color flow cytometry on instruments with only 488 nm excitation source. It requires minimal (0-2%) FL2/FL3 compensation.