Rat Anti-Mouse CD104 (Integrin β4)
CD104 represents the integrin β4 subunit that associates non-covalently with integrin α6 (CD49f) to form the α6β4 integrin heterodimer.
The α6β4 complex is expressed on the basal surface of a variety of epithelial cell types, particularly on stratified squamous epithelia. It is also found in peripheral nerves, in certain subsets of endothelial cells, and on immature thymocytes, and has been found to be associated with a number of malignant tissues.
Hemidesmosomal α6β4 plays an important role in the adhesion of epithelial cells to basement membranes via interactions with laminin and/or kalinin anchoring filaments.
It is not known if the monoclonal antibody 346-11A can block this adhesion.
[Technical Bulletin / References ]
Back to CD Markers and Other Cell Surface Proteins - Specificity Mouse
Rat Anti-Mouse CD104-UNLB
Rat Anti-Mouse CD104-LE/AF
- purified, unlabeled antibody
- fluorescein isothiocyanate-labeled
- tetramethlyrhodamine isothiocyanate
- alkaline phosphatase-labeled
- horseradish peroxidase-labeled
- Texas Red
- R-phycoerythrin/Texas Red
- low endotoxin/azide-free
(SPRD) is a tandem conjugate of R-phycoerythrin and CY
5. It was developed as a reagent for 3-color flow cytometry on instruments with only 488 nm excitation source. It requires minimal (0-2%) FL2/FL3 compensation.
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