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Rat Anti-Mouse CD105 (Endoglin)
ANTIGEN DESCRIPTION
CD105/endoglin is a disulfide-linked type II transmembrane homodimer that is predominantly expressed on vascular endothelial cells. It is also found on pre-erythroblasts, macrophages and lymphoid and myeloid leukemic cells.
[2]
Both mouse and human CD105 exhibit >70% sequence homology in their cytoplasmic domains with type III transforming growth factor β (TGFβ) receptor.
[3]
CD105 has been shown to be one of several receptors for the various isoforms of TGFβ, which in turn is one of a family of proteins involved in regulation of cell differentiation, migration of cells and control of the immune response.
[4]
[Technical Bulletin / References ]
Back to CD Markers and Other Cell Surface Proteins - Specificity Mouse
Cat. No.
Product Description
Clone
Size
USD Price
Order Qty
1860-01
Rat Anti-Mouse CD105-UNLB
MJ7/18
0.5 mg
$218.00
FORMAT ABBREVIATIONS:
UNLB
- purified, unlabeled antibody
FITC
- fluorescein isothiocyanate-labeled
TRITC
- tetramethlyrhodamine isothiocyanate
AP
- alkaline phosphatase-labeled
HRP
- horseradish peroxidase-labeled
BGAL
- B-galactosidase-labeled
TXRD
- Texas Red
TM
BIOT
- biotin-labeled
R-PE
- R-phycoerythrin-labeled
R-PE/TXRD
- R-phycoerythrin/Texas Red
TM
APC
- allophycocyanin
CY3
- Cyanine
TM
3-labeled *
SPRD
- SpectralRed
TM
-labeled *
LE/AF
- low endotoxin/azide-free
CY5
- Cyanine
TM
5-labeled *
R-PE/CY5.5
- R-phycoerythrin/Cyanine
TM
5.5-labeled *
R-PE/CY7
- R-phycoerythrin/Cyanine
TM
7-labeled *
APC/CY5.5
- allophycocyanin/Cyanine
TM
5.5-labeled *
APC/CY7
- allophycocyanin/Cyanine
TM
7-labeled *
FLMA
- fluorescein-5-malemide-labeled
SEPH
- sepharose-labeled
BIMA
- biotin-maleimide-labeled
NOTE:
*SpectralRed
TM
(SPRD) is a tandem conjugate of R-phycoerythrin and CY
TM
5. It was developed as a reagent for 3-color flow cytometry on instruments with only 488 nm excitation source. It requires minimal (0-2%) FL2/FL3 compensation.
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