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Mouse Anti-Chicken CD8α

ANTIGEN DESCRIPTION
n the chicken, the CD8 molecule is present in two forms: (i) a homodimer of two α chains, and (ii) a heterodimer of an α chain and a β chain.[1,2] Chicken CD8 is expressed on approximately 80% of thymocytes, 15% of blood mononuclear cells and 50% of spleen cells, but <1% of cells in the bursa and bone marrow.[1] While the vast majority of CD8+ cells in the thymus, spleen, and blood of adult chickens express both CD8α- and CD8β-chains, a relatively large proportion of the CD8+ TCR-γδ cells in the spleens of embryos and young chicks express only the α-chain of CD8. Among intestinal epithelial lymphocytes, the major CD8+ T cell populations present in mice are conserved, but there is a population of TCR-γδ CD8αβ cells in the chicken that is not found in rodents.[3] MAb EP72 recognizes the CD8α chain.
[Technical Bulletin / References ] Back to CD Markers and Other Cell Surface Proteins - Chicken
 Cat. No.Product DescriptionCloneSize
USD Price
Order Qty
8390-01
 
Mouse Anti-Chicken CD8a-UNLB
EP72 0.5 mg
$240.00
8390-02
 
Mouse Anti-Chicken CD8a-FITC
EP72 0.5 mg
$340.00
8390-08
 
Mouse Anti-Chicken CD8a-BIOT
EP72 0.5 mg
$305.00
8390-09
 
Mouse Anti-Chicken CD8a-R-PE
EP72 0.1 mg
$215.00
FORMAT ABBREVIATIONS:
UNLB - purified, unlabeled antibody
FITC - fluorescein isothiocyanate-labeled
TRITC - tetramethlyrhodamine isothiocyanate
AP - alkaline phosphatase-labeled
HRP - horseradish peroxidase-labeled
BGAL - B-galactosidase-labeled
TXRD - Texas RedTM
BIOT - biotin-labeled
R-PE - R-phycoerythrin-labeled
R-PE/TXRD - R-phycoerythrin/Texas RedTM
APC - allophycocyanin
 CY3 - CyanineTM 3-labeled *
SPRD - SpectralRedTM-labeled *
LE/AF - low endotoxin/azide-free
CY5 - CyanineTM5-labeled *
R-PE/CY5.5 - R-phycoerythrin/CyanineTM5.5-labeled *
R-PE/CY7 - R-phycoerythrin/CyanineTM7-labeled *
APC/CY5.5 - allophycocyanin/CyanineTM5.5-labeled *
APC/CY7 - allophycocyanin/CyanineTM7-labeled *
FLMA - fluorescein-5-malemide-labeled
SEPH - sepharose-labeled
BIMA - biotin-maleimide-labeled
NOTE: *SpectralRedTM (SPRD) is a tandem conjugate of R-phycoerythrin and CYTM5. It was developed as a reagent for 3-color flow cytometry on instruments with only 488 nm excitation source. It requires minimal (0-2%) FL2/FL3 compensation.