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Mouse Anti-Human CD95 (Fas/Apo-1)

ANTIGEN DESCRIPTION
CD95, also known as Fas and Apo-1, is a 40-50 kDa type I transmembrane glycoprotein and a member of the tumor necrosis factor receptor superfamily. It is expressed by activated lymphocytes, monocytes, neutrophils, fibroblasts and cell lines. Fas ligand binding to CD95 induces apoptosis in activated mature lymphocytes thereby playing a role in maintaining peripheral tolerance. Crosslinking of CD95 by the monoclonal antibodies DX2 and DX3 delivers an apoptotic signal to Fas-sensitive cells, indicating that these monoclonal antibodies recognize a functional epitope of CD95.[1-5]
[Technical Bulletin / References ] Back to CD Markers and Other Cell Surface Proteins - Specificity Human
 Cat. No.Product DescriptionCloneSize
USD Price
Order Qty
9735-01
 
Mouse Anti-Human CD95/Fas-UNLB
DX3 0.1 mg
$152.00
9735-02
 
Mouse Anti-Human CD95/Fas-FITC
DX3 100 tests
$225.00
9735-08
 
Mouse Anti-Human CD95/Fas-BIOT
DX3 100 tests
$198.00
9735-09
 
Mouse Anti-Human CD95/Fas-R-PE
DX3 100 tests
$245.00
9735-11
 
Mouse Anti-Human CD95/Fas-APC
DX3 100 tests
$295.00
9735-13
 
Mouse Anti-Human CD95/Fas-SPRD
DX3 100 tests
$275.00
9735-14
 
Mouse Anti-Human CD95/Fas-LE/AF
DX3 0.5 mg
$345.00
FORMAT ABBREVIATIONS:
UNLB - purified, unlabeled antibody
FITC - fluorescein isothiocyanate-labeled
TRITC - tetramethlyrhodamine isothiocyanate
AP - alkaline phosphatase-labeled
HRP - horseradish peroxidase-labeled
BGAL - B-galactosidase-labeled
TXRD - Texas RedTM
BIOT - biotin-labeled
R-PE - R-phycoerythrin-labeled
R-PE/TXRD - R-phycoerythrin/Texas RedTM
APC - allophycocyanin
 CY3 - CyanineTM 3-labeled *
SPRD - SpectralRedTM-labeled *
LE/AF - low endotoxin/azide-free
CY5 - CyanineTM5-labeled *
R-PE/CY5.5 - R-phycoerythrin/CyanineTM5.5-labeled *
R-PE/CY7 - R-phycoerythrin/CyanineTM7-labeled *
APC/CY5.5 - allophycocyanin/CyanineTM5.5-labeled *
APC/CY7 - allophycocyanin/CyanineTM7-labeled *
FLMA - fluorescein-5-malemide-labeled
SEPH - sepharose-labeled
BIMA - biotin-maleimide-labeled
NOTE: *SpectralRedTM (SPRD) is a tandem conjugate of R-phycoerythrin and CYTM5. It was developed as a reagent for 3-color flow cytometry on instruments with only 488 nm excitation source. It requires minimal (0-2%) FL2/FL3 compensation.