Ensuring timely antibody delivery in the face of supply chain challenges - contact us for solutions

Mouse Anti-Mouse NK1.1-PE/CY7 (PK136)

Cat. No.:
1805-17
PE/CY7 Anti-Mouse NK1.1 antibody for use in flow cytometry assays.
$196.00
Size Price (USD) Quantity
0.1 mg $196.00
More Information
Clone PK136
Isotype Mouse (C3H x BALB/c) IgG2aκ
Isotype Control Mouse IgG2a-PE/CY7 (HOPC-1)
Specificity Mouse NK1.1
Alternative Names Ly-55, CD161b/CD161c
Description NK1.1, a member of the NKR-P1 family of cell surface receptors, is a type II integral membrane glycoprotein with a C-type lectin domain. It is expressed as a disulfide-linked homodimer on all NK cells as well as subsets of thymocytes and peripheral T lymphocytes in selected strains of mice (e.g., C57BL/6, NZB, and CE). NK1.1 mediates cellular activation and differentiation, and is thought to have a particular role in generating Th2 cells. This product does not react with NK cells of BALB/c mice.
Immunogen CE mouse spleen enriched for NK-1+ cells and bone marrow cells
Conjugate PE/CY7 (R-phycoerythrin/Cyanine 7)
Buffer Formulation Phosphate buffered saline containing < 0.1% sodium azide and a stabilizer
Clonality Monoclonal
Concentration 0.1 mg/mL
Volume 1.0 mL
Recommended Storage 2-8°C; Avoid exposure to light; Do not freeze
Trademark Information Cy® is a registered trademark of Global Life Sciences Solutions Germany GmbH
Applications Flow Cytometry – Quality tested 1,3-5,8,9
Immunohistochemistry –Reported in literature 8
Immunoprecipitation – Reported in literature 3,4
Depletion – Reported in literature 2,7
Complement Mediated Cell Depletion – Reported in literature 5
Blocking – Reported in literature 4
Activation – Reported in literature 6

RRID Number AB_2795351
Gene ID 17059 (Mouse)
Gene ID Symbol Klrb1c (Mouse)
Gene ID Aliases AI462337; CD161; Klrb1b; Ly-59; Ly55c; Ly59; NK-RP1; NK1.1; NKR-P1.9; NKRP1; NKRP140; Nk-1; Nk-1.2; Nk1; Nk1.2; Nkrp1b; Nkrp1c; ly-55c
UniProt ID P27814 (Mouse)
UniProt Name KLRBC_MOUSE (Mouse)

Certificate of Analysis Lookup

Enter the Catalog Number and Lot Number for the Certificate of Analysis you wish to view


Need help with this product?
or call 800.722.2255
  1. 1. Koo GC, Peppard JR. Establishment of monoclonal anti-Nk-1.1 antibody. Hybridoma. 1984;3:301-3. (Immunogen, FC)
  2. 2. Koo GC, Dumont FJ, Tutt M, Hackett J Jr, Kumar V. The NK-1.1(-) mouse: a model to study differentiation of murine NK cells. J Immunol. 1986;137:3742-7. (Depletion)
  3. 3. Sentman CL, Hackett J Jr, Moore TA, Tutt MM, Bennett M, Kumar V. Pan natural killer cell monoclonal antibodies and their relationship to the NK1.1 antigen. Hybridoma. 1989;8:605-14. (FC, IP)
  4. 4. Kung SK, Su R, Shannon J, Miller RG. The NKR-P1B gene product is an inhibitory receptor on SJL/J NK cells. J Immunol. 1999;162:5876-87. (FC, IP, Block)
  5. 5. Karlhofer FM, Yokoyama WM. Stimulation of murine natural killer (NK) cells by a monoclonal antibody specific for the NK1.1 antigen. IL-2-activated NK cells possess additional specific stimulation pathways. J Immunol. 1991;146:3662-73. (FC, CMDC)
  6. 6. Reichlin A, Yokoyama WM. Natural killer cell proliferation induced by anti-NK1.1 and IL-2. Immunol Cell Biol. 1998;76:143-52. (Activ)
  7. 7. Sharma N, He Q, Sharma RP. Amelioration of fumonisin B1 hepatotoxicity in mice by depletion of T cells with anti-Thy-1.2. Toxicology. 2006;223:191-201. (Depletion)
  8. 8. Al-Falahi Y, Sand KL, Knudsen E, Damaj BB, Rolin J, Maghazachi AA. Splenic natural killer cell activity in two models of experimental neurodegenerative diseases. J Cell Mol Med. 2009;13:2693-703. (FC, IHC)
  9. 9. Freitas CS, Dalmau SR, Abdelhay E. Differential expression of notch signaling-related transcripts accompanies pro-thymocyte proliferation and phenotype transition induced by epidermal growth factor plus insulin in fetal thymus organ cultures. Mem Inst Oswaldo Cruz. 2004;99:381-88. (FC)
See All References