Mouse Anti-Human CD79b-SPRD

Cat. No.
9710-13  
Size
100 tests  
Price (USD)
$235.00 
Clone CB3-1
Isotype Mouse (BALB/c) IgG1κ
Isotype Control Mouse IgG1-SPRD
Immunogen Ramos B cells
Specificity Human CD79b
Alternalte Name(s) B29, Igβ
Description CD79 is a disulfide-linked heterodimer composed of an α chain (CD79a) and a β chain (CD79b) that associates non-covalently with membrane immunoglobulin to form the B cell receptor (BCR) complex. Its expression is restricted to B lymphocytes first appearing on the surface at the pro-B cell stage and remaining through all stages of B cell differentiation prior to plasma cells. Crosslinking of the BCR leads to B cell activation. The monoclonal antibody CB3-1 reacts with the β chain of CD79.
Format/Conjugate SPRD (R-phycoerythrin/Cyanine 5)
Buffer Formulation Phosphate buffered saline containing 0.1% sodium azide and a stabilizer
Volume 1.0 mL
Storage & Handling 2-8°C; Avoid exposure to light; Do not freeze
Please refer to product specific SDS
Applications
Applications for relevant formats of this clone include -
Flow Cytometry – Quality tested 1,3-5
Immunoprecipitation – Reported in literature 1,2
Western Blot – Reported in literature 1
Recommended Dilutions Please refer to product specific Technical Bulletin
RRID AB_2797072
Gene ID
974 (Human)
Gene Symbol
CD79B (Human)
Gene Aliases AGM6; B29; IGB
Uniprot ID
P40259 (Human)
Uniprot Name
  • Human peripheral blood lymphocytes were stained with Mouse Anti-Human CD79b-APC (SB Cat. No. 9710-11) and Mouse Anti-Human CD19-FITC (SB Cat. No. 9340-02).

Human peripheral blood lymphocytes were stained with Mouse Anti-Human CD79b-APC (SB Cat. No. 9710-11) and Mouse Anti-Human CD19-FITC (SB Cat. No. 9340-02).
 
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References
1. Nakamura T, Kubagawa H, Cooper MD. Heterogeneity of immunoglobulin-associated molecules on human B cells identified by monoclonal antibodies. Proc Natl Acad Sci USA. 1992;89:8522-6. (Immunogen, IP, WB, FC)
2. Lévéille C, Castaigne J, Charron D, Al-Daccak R. MHC class II isotype-specific signaling complex on human B cells. Eur J Immunol. 2002;32:2282-91. (IP)
3. Lanvin O, Guglielmi P, Fuentes V, Gouilleux-Gruart V, Mazière C, Bissac E, et al. TGF-β1 modulates Fas (APO-1/CD95)-mediated apoptosis of human pre-B cell lines. Eur J Immunol. 2003;33:1372-81. (FC)
4. Demurtas A, Stacchini A, Aliberti S, Chiusa L, Chiarle R, Novero D. Tissue flow cytometry immunophenotyping in the diagnosis and classification of non-Hodgkin's lymphomas: a retrospective evaluation of 1,792 cases. Cytometry B Clin Cytom. 2013;84B:82-95. (FC)
5. Stacchini A, Aliberti S, Pacchioni D, Demurtas A, Isolato G, Gazzera C, et al. Flow cytometry significantly improves the diagnostic value of fine needle aspiration cytology of lymphoproliferative lesions of salivary glands. Cytopathology. 2014;25:231-40. (FC)
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