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Hamster Anti-Mouse CD79b-LE/AF (HM79-12)

Cat. No.:
1830-14
Low Endotoxin/Azide Free Anti-Mouse CD79b antibody for use in flow cytometry, western blot, and immunoprecipitation assays.
$363.00
Size Price (USD) Quantity
0.5 mg $363.00
More Information
Clone HM79-12
Isotype Hamster (Armenian) IgG1
Isotype Control Hamster IgG-LE/AF
Specificity Mouse CD79b
Alternative Names B29, Igβ
Description Murine CD79 is a disulfide-linked heterodimer composed of an α chain (CD79a) and a β chain (CD79b) that associates non-covalently with membrane immunoglobulin (Ig) to form the B cell receptor (BCR) complex. Its expression is restricted to B lymphocytes first appearing on the surface at the pro-B cell stage prior to productive Ig gene rearrangements and remaining through all stages of B-cell differentiation prior to plasma cells. It has been proposed that the CD79 complex on pro-B cell surfaces may function to induce early B-cell differentiation.
Immunogen CD79α/CD79β heterodimers purified from mouse (BALB/c x NZB)F1 B cell lymphoma cells, WEHI231
Conjugate LE/AF (Low Endotoxin/Azide Free)
Buffer Formulation Phosphate buffered saline, pH 7.4
Clonality Monoclonal
Concentration 0.5 mg/mL
Volume 1.0 mL
Recommended Storage 2-8°C; Handle under aseptic conditions
Applications Flow Cytometry – Quality tested 1-3
Immunoprecipitation – Reported in literature 1,2
Western Blot – Reported in literature 1

RRID Number AB_2795408
Gene ID 15985 (Mouse)
Gene ID Symbol Cd79b (Mouse)
Gene ID Aliases B29; Ig-beta; Igb; Igbeta
UniProt ID P15530 (Mouse)
UniProt Name CD79B_MOUSE (Mouse)

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  1. 1. Koyama M, Ishihara K, Karasuyama H, Cordell JL, Iwamoto A, Nakamura T. CD79α/CD79β heterodimers are expressed on pro-B cell surfaces without associated μ heavy chain. Int Immunol. 1997;9:1767-72. (Immunogen, FC, IP, WB)
  2. 2. Kato I, Miyazaki T, Nakamura T, Kudo A. Inducible differentiation and apoptosis of the pre-B cell receptor-positive pre-B cell line. Int Immunol. 2000;12:325-34. (IP, FC)
  3. 3. McHeyzer-Williams LJ, Cool M, McHeyzer-Williams MG. Antigen-specific B cell memory: expression and replenishment of a novel b220(-) memory b cell compartment. J Exp Med. 2000;191:1149-65. (FC)