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Mouse Anti-GSK-3α-HRP (SBGSK3α2)
Cat. No.:
10905-05
HRP Anti-GSK-3α antibody for use in western blot assays.
$396.00
| Clone | SBGSK3α2 |
|---|---|
| Isotype | Mouse (BALB/c) IgG2aκ |
| Isotype Control | Mouse IgG2a-HRP (HOPC-1) |
| Specificity | Human/Mouse GSK-3α |
| Alternative Names | Glycogen synthase kinase-3 alpha |
| Description | Glycogen synthase kinase-3 (GSK-3) is a protein serine kinase that phosphorylates glycogen synthase and thereby inactivates it. Insulin stimulates the dephosphorylation of glycogen synthase at the sites phosphorylated by GSK-3 and subsequently inhibits GSK-3 acutely leading to the stimulation of glycogen synthesis. GSK-3 signaling is performed by two isoforms, GSK-3α and GSK-3β. The two isoforms share 97% sequence similarity within their catalytic domains. GSK-3 has also been shown to play a role in protein synthesis, cell adhesion, cell proliferation, cell differentiation, microtubule dynamics, and cell motility. |
| Immunogen | Recombinant N-terminal GSK-3α |
| Conjugate | HRP (Horseradish Peroxidase) |
| Buffer Formulation | 50% Glycerol/50% Phosphate buffered saline, pH 7.4 |
| Clonality | Monoclonal |
| Concentration | Lot specific |
| Volume | 1.0 mL |
| Recommended Storage | 2-8°C |
| Applications | Western Blot – Quality tested 1 |
| RRID Number | AB_2794535 |
| Gene ID | 2931 (Human) 606496 (Mouse) |
| Gene ID Symbol | GSK3A (Human) Gsk3a (Mouse) |
| Gene ID Aliases | 2700086H06Rik |
| UniProt ID | P49840 (Human) Q2NL51 (Mouse) |
| UniProt Name | GSK3A_HUMAN (Human) GSK3A_MOUSE (Mouse) |
Documentation
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