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Mouse Anti-Human GSK-3β-UNLB (5D6)

Cat. No:
10915-01
Purified Anti-GSK-3β antibody for use in ELISA, western blot, and immunoprecipitation assays.
$315.00
Size Price (USD) Quantity
0.1 mg $315.00
More Information
Clone 5D6
Isotype Mouse (BALB/c) IgG2bκ
Isotype Control Mouse IgG2b-UNLB (A-1)
Specificity Human GSK-3β
Alternative Names Glycogen synthase kinase-3 beta
Description Glycogen synthase kinase-3 (GSK-3) is a protein serine kinase that phosphorylates glycogen synthase and thereby inactivates it. Insulin stimulates the dephosphorylation of glycogen synthase at the sites phosphorylated by GSK-3 and subsequently inhibits GSK-3 acutely leading to the stimulation of glycogen synthesis. GSK-3 signaling is performed by two isoforms, GSK-3α and GSK-3β. The two isoforms share 97% sequence similarity within their catalytic domains. GSK-3 has also been shown to play a role in protein synthesis, cell adhesion, cell proliferation, cell differentiation, microtubule dynamics, and cell motility.
Immunogen Recombinant N-terminal GSK-3β
Conjugate UNLB (Unconjugated)
Buffer Formulation Borate buffered saline, pH 8.2
Clonality Monoclonal
Concentration 0.5 mg/mL
Volume 0.2 mL
Recommended Storage 2-8°C
Applications Western Blot – Quality tested
Immunoprecipitation – Quality tested 1,2
ELISA 3

RRID Number AB_2794546
Gene ID 2932 (Human)
Gene ID Symbol GSK3B (Human)
UniProt ID P49841 (Human)
UniProt Name GSK3B_HUMAN (Human)

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  1. 1. Meares GP, Zmijewska AA, Jope RS. HSP105 interacts with GRP78 and GSK3 and promotes ER stress-induced caspase-3 activation. Cell Signal. 2008;20:347-58. (IP)
  2. 2. Sun M, Song L, Li Y, Zhou T, Jope RS. Identification of an antiapoptotic protein complex at death receptors. Cell Death Differ. 2008;15:1887-1900. (IP)
  3. 3. SouthernBiotech unpublished data (ELISA)