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Mouse Anti-GSK-3α-SEPH (SBGSK3α4)

Cat. No.:
10910-25
Agarose Anti-GSK-3α antibody for use in immunoprecipitation assays.
$425.00
Size Price (USD) Quantity
50 tests $425.00
More Information
Clone SBGSK3α4
Isotype Mouse (BALB/c) IgG2aκ
Isotype Control 0103-25
Specificity Human/Mouse GSK-3α
Alternative Names Glycogen synthase kinase-3 alpha
Description Glycogen synthase kinase-3 (GSK-3) is a protein serine kinase that phosphorylates glycogen synthase and thereby inactivates it. Insulin stimulates the dephosphorylation of glycogen synthase at the sites phosphorylated by GSK-3 and subsequently inhibits GSK-3 acutely leading to the stimulation of glycogen synthesis. GSK-3 signaling is performed by two isoforms, GSK-3α and GSK-3β. The two isoforms share 97% sequence similarity within their catalytic domains. GSK-3 has also been shown to play a role in protein synthesis, cell adhesion, cell proliferation, cell differentiation, microtubule dynamics, and cell motility.
Immunogen Recombinant N-terminal GSK-3α
Conjugate SEPH (Agarose)
Buffer Formulation Borate buffered saline, pH 8.2
Clonality Monoclonal
Concentration Lot specific
Volume 2.0 mL
Recommended Storage 2-8°C
Trademark Information Sepharose® is a registered trademark of Cytiva Bioprocess R&D AB
Applications Western Blot – Quality tested 3
Immunoprecipitation – Quality tested 1,2

RRID Number AB_2794540
Gene ID 2931 (Human)
606496 (Mouse)
Gene ID Symbol GSK3A (Human)
Gsk3a (Mouse)
Gene ID Aliases 2700086H06Rik
UniProt ID P49840 (Human)
Q2NL51 (Mouse)
UniProt Name GSK3A_HUMAN (Human)
GSK3A_MOUSE (Mouse)

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  1. 1. Meares GP, Zmijewska AA, Jope RS. HSP105 interacts with GRP78 and GSK3 and promotes ER stress-induced caspase-3 activation. Cell Signal. 2008;20:347-58. (IP)
  2. 2. Sun M, Song L, Li Y, Zhou T, Jope RS. Identification of an antiapoptotic protein complex at death receptors. Cell Death Differ. 2008;15:1887-1900. (IP)
  3. 3. SouthernBiotech published data