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Mouse Anti-Human GSK-3β-UNLB (3A11)

Cat. No.:
10920-01
Purified Anti-GSK-3β antibody for use in ELISA and western blot assays.
$300.00
Size Price (USD) Quantity
0.1 mg $300.00
More Information
Clone 3A11
Isotype Mouse (BALB/c) IgG2aκ
Isotype Control Mouse IgG2a-UNLB (HOPC-1)
Specificity Human GSK-3β
Alternative Names Glycogen synthase kinase-3 beta
Description Glycogen synthase kinase-3 (GSK-3) is a protein serine kinase that phosphorylates glycogen synthase and thereby inactivates it. Insulin stimulates the dephosphorylation of glycogen synthase at the sites phosphorylated by GSK-3 and subsequently inhibits GSK-3 acutely leading to the stimulation of glycogen synthesis. GSK-3 signaling is performed by two isoforms, GSK-3α and GSK-3β. The two isoforms share 97% sequence similarity within their catalytic domains. GSK-3 has also been shown to play a role in protein synthesis, cell adhesion, cell proliferation, cell differentiation, microtubule dynamics, and cell motility.
Immunogen Recombinant N-terminal GSK-3β
Conjugate UNLB (Unconjugated)
Buffer Formulation Borate buffered saline, pH 8.2
Clonality Monoclonal
Concentration 0.5 mg/mL
Volume 0.2 mL
Recommended Storage 2-8°C
Applications ELISA – Quality tested
Immunoblotiing – Reported in literature 1

RRID Number AB_2794548
Gene ID 2932 (Human)
Gene ID Symbol GSK3B (Human)
UniProt ID P49841 (Human)
UniProt Name GSK3B_HUMAN (Human)

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  1. 1. Sun M, Song L, Li Y, Zhou T, Jope RS. Identification of an antiapoptotic protein complex at death receptors. Cell Death Differ. 2008;15:1887-1900. (WB)