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Mouse Anti-Human TLR2-LE/AF (2B4A1)

Cat. No.:
11000-14
Low Endotoxin/Azide Free Anti-Human TLR2 antibody for use in flow cytometry assays.
$230.00
Size Price (USD) Quantity
0.1 mg $230.00
More Information
Clone 2B4A1
Isotype Mouse (BALB/c) IgG2aκ
Isotype Control Mouse IgG2a-LE/AF (HOPC-1)
Specificity Human/Canine TLR2
Alternative Names Toll-like receptor 2, CD282, TIL4
Description The Toll-like receptor (TLR) family is comprised of type I transmembrane proteins characterized by an extracellular leucine-rich domain and a cytoplasmic tail that contains a conserved region call the Toll/IL-1 (TIR) domain. First discovered in Drosophila, TLRs recognize specific molecular patterns that are present in microbial components and respond to these components in order eliminate or limit invading microbes. TLR2 recognizes and is activated by components from a broad variety of microorganisms including lipoproteins from Gram-negative and Gram-positive bacteria, lipoteichoic acid from Gram-positive bacteria, lipoarabinomannan from mycobacteria, and zymosan from yeast. TLR2 has been reported to functionally associate with TLR1 and TLR6 in order to recognize various lipopeptides.
Immunogen Recombinant TLR2
Conjugate LE/AF (Low Endotoxin/Azide Free)
Buffer Formulation Phosphate buffered saline, pH 7.4
Clonality Monoclonal
Concentration 0.5 mg/mL
Volume 0.2 mL
Recommended Storage 2-8°C; Handle under aseptic conditions
Applications Flow Cytometry – Quality tested 1-3

RRID Number AB_2794569
Gene ID 7097 (Human)
448807 (Canine)
Gene ID Symbol TLR2 (Human)
TLR2 (Canine)
Gene ID Aliases CD282; TIL4
UniProt ID O60603 (Human)
Q689D1 (Canine)
UniProt Name TLR2_HUMAN (Human)
TLR2_CANLF (Canine)

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  1. 1. Amorim IF, Silva SM, Figueiredo MM, Moura EP, Castro RS, Lima TK, et al. Toll receptors type-2 and CR3 expression of canine monocytes and its correlation with immunohistochemistry and xenodiagnosis in visceral leishmaniasis. PLoS One. 2011;6(11):e27679. (FC, Canine Reactivity)
  2. 2. Rolf N, Kariminia A, Ivison S, Reid GS, Schultz KR. Heterodimer-specific TLR2 stimulation results in divergent functional outcomes in B-cell precursor acute lymphoblastic leukemia. Eur J Immunol. 2015;45:1980-90. (FC)
  3. 3. Lashkari B, Anumba DO. Estradiol alters the immune-responsiveness of cervical epithelial cells stimulated with ligands of Toll-like receptors 2 and 4. PLoS One. 2017;12(3):e0173646. (FC)