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Rat Anti-Mouse CD94-PE (18d3)

Cat. No.:
1809-09
PE Anti-Mouse CD94 antibody for use in flow cytometry assays.
$165.00
Size Price (USD) Quantity
0.1 mg $165.00
More Information
Clone 18d3
Isotype Rat (Lewis) IgG2aκ
Isotype Control Rat IgG2a-PE (KLH/G2a-1-1)
Specificity Mouse CD94
Alternative Names Kp43, KLRD1
Description The monoclonal antibody 18d3 reacts with the mouse CD94 receptor subunit, a type II transmembrane glycoprotein. CD94 is expressed on the surface of NK cells, NK T cells, and some memory phenotype CD8+ cells. When CD94 is paired with NKG2A, C, or E subunit, it binds the nonclassical MHC class Ib molecule Qa-1b and results in a CD94high population by flow cytometry. Approximately half of NK cells do not express NKG2A, C or E; these cells express CD94 on the surface in a form that does not bind Qa-1b and is believed to be nonfunctional, producing a CD94low population by flow cytometry. CD94 is thought to play a role in the adhesion and activation of the NK cell lineage.
Immunogen CHO cells transfected with the B6 allele of CD94
Conjugate PE (R-phycoerythrin)
Buffer Formulation Phosphate buffered saline containing < 0.1% sodium azide and a stabilizer
Clonality Monoclonal
Concentration 0.1 mg/mL
Volume 1.0 mL
Recommended Storage 2-8°C; Avoid exposure to light; Do not freeze
Applications Flow Cytometry – Quality tested 1-3

RRID Number AB_2795375
Gene ID 16643 (Mouse)
Gene ID Symbol Klrd1 (Mouse)
Gene ID Aliases CD94
UniProt ID O54707 (Mouse)
UniProt Name KLRD1_MOUSE (Mouse)

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  1. 1. Vance RE, Jamieson AM, Raulet DH. Recognition of the class Ib molecule Qa-1b by putative activating receptors CD94/NKG2C and CD94/NKG2E on mouse natural killer cells. J Exp Med. 1999;190:1801-12. (Immunogen, FC)
  2. 2. Beyersdorf NB, Ding X, Karp K, Hanke T. Expression of inhibitory "killer cell lectin-like receptor G1" identifies unique subpopulations of effector and memory CD8 T cells. Eur J Immunol. 2001;31:3443-52. (FC)
  3. 3. Vance RE, Jamieson AM, Cado D, Raulet DH. Implications of CD94 deficiency and monoallelic NKG2A expression for natural killer cell development and repertoire formation. Proc Natl Acad Sci USA. 2002;99:868-73. (FC)