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IgA Isotype Controls

Immunoglobulin A (IgA) is the predominant immunoglobulin in secretions and in the gastrointestinal and urogenital tracts. IgA makes up approximately 15% of serum immunoglobulins. IgA in serum is typically monomeric but dimeric in secretions (e.g., saliva, tears, colostrums, mucus, sweat, and gastric fluid) where it is found as a dimer connected by a J chain. IgA provides the primary defense mechanism against some local infections because of its abundance in mucosal secretions.

Two IgA subclasses exist in humans, IgA1 and IgA2, while mice have only one subclass. IgA1 is the prominent subclass of the total IgA concentration in human serum (~85%) with IgA2 representing approximately 15% of the total IgA in serum. IgA2 plays a critical role in the mucosa of the airways, eyes, and gastrointestinal tract to fight infectious antigens. SouthernBiotech produces and validates an extensive range of human and mouse IgA purified immunoglobulins available in unconjugated and conjugated formats, for use as standards and negative controls in applications such as ELISA, flow cytometry, immunofluorescence, and functional assays.

Items 1-12 of 16

Set Ascending Direction
  1. 0106-13
    Mouse IgA-PE/CY5 (SPRD) for use as a control in flow cytometry assays.

    100 tests
    Monoclonal
    Mouse
    SPRD
    FC
  2. 0155L-01
    Purified Human IgA Lambda for use as a standard in ELISA.

    0.5 mg
    Purified from myeloma serum
    Human
    UNLB
    ELISA
  3. 0155L-05
    Human IgA Lambda-HRP for use as a control in ELISA assays.

    1.0 mL
    Purified from myeloma serum
    Human
    HRP
    ELISA
  4. 0106-14
    Low Endotoxin/Azide Free Mouse IgA for use as a control in flow cytometry and in vivo assays and as a standard in ELISA.

    0.5 mg
    Monoclonal
    Mouse
    LE/AF
    ELISA, FC, In vivo Control
  5. 0106-18
    Mouse IgA-APC/CY5.5 for use as a control in flow cytometry assays.

    100 tests
    Monoclonal
    Mouse
    APC/CY5.5
    FC
  6. 0155K-04
    Human IgA Kappa-AP for use as a control in ELISA assays.

    1.0 mL
    Purified from myeloma serum
    Human
    AP
    ELISA
  7. 0155L-04
    Human IgA Lambda-AP for use as a control in ELISA assays.

    1.0 mL
    Purified from myeloma serum
    Human
    AP
    ELISA
  8. 0106-02
    Mouse IgA-FITC for use as a control in flow cytometry assays.

    100 tests
    Monoclonal
    Mouse
    FITC
    FC, FLISA
  9. 0106-09
    Mouse IgA-PE for use as a control in flow cytometry assays.

    100 tests
    Monoclonal
    Mouse
    PE
    FC, FLISA
  10. 0106-11
    Mouse IgA-APC for use as a control in flow cytometry assays.

    100 tests
    Monoclonal
    Mouse
    APC
    FC, FLISA
  11. 0106-01
    Purified Mouse IgA for use as a control in flow cytometry assays and as a standard in ELISA.

    1.0 mg
    Monoclonal
    Mouse
    UNLB
    ELISA, FC
  12. 0106-19
    Mouse IgA-APC/CY7 for use as a control in flow cytometry assays.

    100 tests
    Monoclonal
    Mouse
    APC/CY7
    FC
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