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IgG / IgY Isotype Controls

Immunoglobulin G (IgG) is the most abundant Ig isotype in serum and makes up approximately 80% of all serum immunoglobulins. In humans, there are four subclasses of IgG (IgG1, IgG2, IgG3, and IgG4), which are defined in the order of their relative concentration in normal serum. In mice, the IgG subclasses are designated as IgG1, IgG2a/c, IgG2b, and IgG3. Although structurally very similar, the subclasses differ in the number of disulfide bonds, length, and flexibility of the hinge region, as well as their functions. The IgG molecule consists of two heavy and two light chains, kappa or lambda.

IgY is the major circulating antibody found in birds, reptiles, amphibia, and lungfish and the counterpart to mammalian IgG as it has the same general structure. High levels of IgG antibodies are induced following the initial IgM response in a typical immune response to antigens. Due to its relative abundance and excellent specificity toward antigens, IgG is the primary antibody used in immunological research and clinical diagnostics. SouthernBiotech produces and validates an extensive range of monoclonal and polyclonal IgG (including IgG subclass and IgG isotype controls), and IgY purified immunoglobulins. Human, mouse, rabbit, goat, rat, hamster, canine, donkey, sheep, monkey, porcine, and chicken immunoglobulins are available in unconjugated and conjugated formats for use as standards and negative controls in applications such as ELISA, flow cytometry, immunofluorescence, and functional assays.

Items 1-12 of 221

Set Ascending Direction
  1. 0102-01
    Purified Mouse IgG1 for use as a control in flow cytometry, immunohistochemistry / immunocytochemistry, western blot, multiplex, and in vitro assays and as a standard in ELISA.

    1.0 mg
    Monoclonal
    Mouse
    UNLB
    Block, ICC, IHC-FS, IHC-PS, ELISA, FC, In vitro control, Multiplex, WB
  2. 0102-02
    Mouse IgG1-FITC for use as a control in flow cytometry and immunohistochemistry / immunocytochemistry assays.

    100 tests
    Monoclonal
    Mouse
    FITC
    ICC, IHC-FS, IHC-PS, FC, FLISA, WB
  3. 0102-05
    Mouse IgG1-HRP for use as a control in immunohistochemistry / immunocytochemistry assays.

    1.0 mL
    Monoclonal
    Mouse
    HRP
    ICC, IHC-FS, IHC-PS, ELISA, WB
  4. 0102-27
    Mouse IgG1-Alexa Fluor® 700 for use as a control in flow cytometry assays.

    100 tests
    Monoclonal
    Mouse
    AF700
    FC
  5. 0103-04
    Mouse IgG2a-AP for use as a control in immunohistochemistry / immunocytochemistry assays.

    1.0 mL
    Monoclonal
    Mouse
    AP
    ICC, IHC-FS, IHC-PS, ELISA, WB
  6. 0103-10
    Mouse IgG2a-PE/Texas Red for use as a control in flow cytometry assays.

    100 tests
    Monoclonal
    Mouse
    PE/TXRD
    FC
  7. 0103-30
    Mouse IgG2a-Alexa Fluor® 488 for use as a control in flow cytometry and immunohistochemistry / immunocytochemistry assays.

    100 tests
    Monoclonal
    Mouse
    AF488
    ICC, IHC-FS, IHC-PS, FC, FLISA, WB
  8. 0104-12
    Mouse IgG2b-CY3 for use as a control in flow cytometry and immunohistochemistry assays.

    100 tests
    Monoclonal
    Mouse
    CY3
    IHC-FS, FC, FLISA
  9. 0104-18
    Mouse IgG2b-APC/CY5.5 for use as a control in flow cytometry assays.

    100 tests
    Monoclonal
    Mouse
    APC/CY5.5
    FC
  10. 0105-02
    Mouse IgG3-FITC for use as a control in flow cytometry and immunocytochemistry assays.

    100 tests
    Monoclonal
    Mouse
    FITC
    ICC, FC, FLISA
  11. 0105-04
    Mouse IgG3-AP for use as a control in immunocytochemistry assays.

    1.0 mL
    Monoclonal
    Mouse
    AP
    ICC, ELISA
  12. 0105-14
    Low Endotoxin/Azide Free Mouse IgG3 for use as a control in flow cytometry, immunocytochemistry, immunoprecipitation, and in vitro assays and as a standard in ELISA.

    0.5 mg
    Monoclonal
    Mouse
    LE/AF
    ICC, IP, ELISA, FC, In vitro control
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