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Mouse Anti-Human Smac/DIABLO-UNLB (2D12)
Cat. No.:
11070-01
Purified Anti-Human Smac/DIABLO antibody for use in ELISA and western blot assays.
$330.00
| Clone | 2D12 |
|---|---|
| Isotype | Mouse (BALB/c) IgG2bκ |
| Isotype Control | Mouse IgG2b-UNLB (A-1) |
| Specificity | Human Smac/DIABLO |
| Alternative Names | SMAC3, DIABLO-S , FLJ10537, FLJ25049, 0610041G12Rik |
| Description | Smac/DIABLO (second mitochondria-derived activator of caspase/direct IAP-binding protein with low PI) is a mitochondrial protein that functions as a regulatory component during apoptosis. It is encoded by a nuclear gene and is subsequently imported into the mitochondria where the N-terminus is removed generating the mature form of the molecule. Smac/DIABLO has been shown to neutralize the antiapoptotic effect of the inhibitor of apoptosis protein (IAP) family, a major group of apoptosis regulators that have been shown to directly block caspase activity thereby blocking apoptosis. |
| Immunogen | Recombinant Smac/DIABLO |
| Conjugate | UNLB (Unconjugated) |
| Buffer Formulation | Borate buffered saline, pH 8.2 |
| Clonality | Monoclonal |
| Concentration | 0.5 mg/mL |
| Volume | 0.2 mL |
| Recommended Storage | 2-8°C |
| Applications |
ELISA – Quality tested Western Blot 1 |
| RRID Number | AB_2794600 |
| Gene ID |
56616 (Human) |
| Gene ID Symbol |
DIABLO (Human) |
| Gene ID Aliases | DFNA64; SMAC |
| UniProt ID |
Q9NR28 (Human |
| UniProt Name |
DBLOH_HUMAN (Human) |
Documentation
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