Ensuring timely antibody delivery in the face of supply chain challenges - contact us for solutions

Mouse Anti-Human TIMP-4-HRP (SB30c)

Cat. No.:
HRP Anti-Human TIMP-4 antibody for use in immunohistochemistry / immunocytochemistry, ELISA, and western blotting assays.
Size Price (USD) Quantity
1.0 mL $396.00
More Information
Clone SB30c
Isotype Mouse (BALB/c) IgG2aκ
Isotype Control Mouse IgG2a-HRP (HOPC-1)
Specificity Human/Mouse/Rat TIMP-4
Alternative Names Tissue inhibitor of metalloproteinase 4
Description Tissue inhibitors of matrix metalloproteinases (TIMPs) constitute a family of secreted multifunctional proteins which are classified based on structural similarity to each other as well as their ability to inhibit matrix metalloproteinases (MMPs). TIMPs play a critical role in ECM homeostasis but have also been shown to have erythroid-potentiating and cell growth-promoting activities. TIMP-4, unlike TIMP-1, TIMP-2 and TIMP-3, shows restricted localization to cardiac, neural, breast, and muscle tissue. Cardiospecific TIMP-4 seems to play a significant role in regulating the normal cell phenotype since reduced levels elicit cellular transformation.
Immunogen Recombinant human TIMP-4 (a.a. 35-224)
Conjugate HRP (Horseradish Peroxidase)
Buffer Formulation 50% Glycerol/50% Phosphate buffered saline, pH 7.4
Clonality Monoclonal
Concentration Lot specific
Volume 1.0 mL
Recommended Storage 2-8°C
Applications Western Blot – Quality tested 1-3
Immunohistochemistry-Paraffin Sections 4
Immunocytochemistry 4

RRID Number AB_2794708
Gene ID 7079 (Human)
110595 (Mouse)
680130 (Rat)
Gene ID Symbol TIMP4 (Human)
Timp4 (Mouse)
Timp4 (Rat)
Gene ID Aliases TIMP-4; Timp-4
UniProt ID Q99727 (Human)
Q9JHB3 (Mouse)
P81556 (Rat)
UniProt Name TIMP4_HUMAN (Human)

Certificate of Analysis Lookup

Enter the Catalog Number and Lot Number for the Certificate of Analysis you wish to view

Need help with this product?
or call 800.722.2255
  1. 1. Alarab M, Kufaishi H, Lye S, Drutz H, Shynlova O. Expression of extracellular matrix-remodeling proteins is altered in vaginal tissue of premenopausal women with severe pelvic organ prolapse. Reprod Sci. 2014;21:704-15. (WB)
  2. 2. Zambirinis CP, Levie E, Nguy S, Avanzi A, Barilla R, Xu Y, et al. TLR9 ligation in pancreatic stellate cells promotes tumorigenesis. J Exp Med. 2015;212:2077-94. (WB, Mouse Reactivity)
  3. 3. Ketsawatsomkron P, Keen HL, Davis DR, Lu K, Stump M, De Silva TM, et al. Protective role for tissue inhibitor of metalloproteinase-4, a novel peroxisome proliferator-activated receptor-γ target gene, in smooth muscle in deoxycorticosterone acetate-salt hypertension. Hypertension. 2016;67:214-22. (WB, Mouse & Rat Reactivity)
  4. 4. SouthernBiotech published data (IHC-PS, ICC)
  5. 5. SouthernBiotech unpublished data (ELISA)
See All References