ApoScreen® Annexin V-UNLB (Insect-expressed)
Purified ® Annexin V for use in flow cytometry and immunocytochemistry assays.
|Description||ApoScreen® Annexin V (SB Cat. No. 10039) is a recombinant protein that is expressed in eukaryotic cells. A number of changes in cell structure occur during apoptosis. One major change is the loss of membrane phospholipid asymmetry, with translocation of phosphatidylserine (PS) from the inner leaflet of the phospholipid bilayer to the external surface. Annexin V, a member of the annexin family of calcium-dependent phospholipid binding proteins, has a high affinity for phosphatidylserine (PS)-containing phospholipid bilayers. Conjugated Annexin V can be used to monitor changes in cell membrane phospholipid asymmetry, thereby providing a convenient tool for detection of apoptotic cells.|
|Buffer Formulation||Lyophilized from phosphate buffered saline and 1 mM EDTA|
|Trademark Information||ApoScreen® is a registered trademark of Southern Biotechnology Associates, Inc.|
Flow Cytometry – Quality tested 1|
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- 1. Peterson LF, Mitrikeska E, Giannola D, Lui Y, Sun H, Bixby D, et al. p53 stabilization induces apoptosis in chronic myeloid leukemia blast crisis cells. Leukemia. 2011;25:761-9. (FC)
- 2. SouthernBiotech published data (ICC)