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Mouse Anti-Human IL-33-BIOT (SB127c)

Cat. No.:
Biotin Anti-Human IL-33 antibody for use in ELISA assays.
Size Price (USD) Quantity
0.5 mg $369.00
More Information
Clone SB127c
Isotype Mouse (BALB/c) IgG2bκ
Isotype Control Mouse IgG2b-BIOT (A-1)
Specificity Human IL-33
Alternative Names Interleukin-33, IL-1F11, NF-HEV
Description Interleukin-33 (IL-33), also known as NF-HEV, is a 30 kDa protein and a member of the IL-1 family. This pro-inflammatory cytokine is produced by a variety of cells but is primarily expressed by endothelial and smooth muscle cells in the vasculature and airways. IL-33 binds to the ST2 receptor on target cells which results in the activation of multiple signaling pathways including NF-κB and MAP kinases. Studies have shown that IL-33 promotes T helper type 2 (Th2) cell-mediated immune responses and upregulates production of Th2 associated cytokines including IL-4, IL-5, and IL-13. In vivo administration of this cytokine in mice results in eosinophilia and splenomegaly as well as induced severe pathological changes in the lungs, gastrointestinal tract, and other mucosal organs.
Immunogen E. coli-expressed human IL-33
Conjugate BIOT (Biotin)
Buffer Formulation Phosphate buffered saline containing < 0.1% sodium azide
Clonality Monoclonal
Concentration 0.5 mg/mL
Volume 1.0 mL
Recommended Storage 2-8°C
Applications ELISA – Quality tested

Note – May be paired with the purified clone SB127j (SB Cat. No. 15710-01) in a sandwich ELISA

RRID Number AB_2794939
Gene ID 90865 (Human)
Gene ID Symbol IL33 (Human)
Gene ID Aliases C9orf26; DVS27; IL1F11; NF-HEV; NFEHEV
UniProt ID O95760 (Human
UniProt Name IL33_HUMAN (Human)

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