Rat Anti-Mouse CD45RB-PE

Cat. No.
1675-09  
Size
0.1 mg   		Price (USD)
$95.00 
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Clone C363.16A
Isotype Rat IgG2aκ
Isotype Control Rat IgG2a-PE
Immunogen Cloned mouse Th cell line
Specificity Mouse CD45RB
Description CD45RB represents an exon B-dependent form of CD45 glycoprotein. It is expressed at high density on peripheral B cells, the suppressor/cytotoxic subpopulation of T lymphocytes, a subset of helper T cells, most thymocytes, and at low density on macrophages and dendritic cells.
Format/Conjugate PE (R-phycoerythrin)
Buffer Formulation Phosphate buffered saline containing < 0.1% sodium azide and a stabilizer
Concentration 0.1 mg/mL
Volume 1.0 mL
Storage & Handling 2-8°C; Avoid exposure to light; Do not freeze
Please refer to product specific SDS
Applications
Applications for relevant formats of this clone include -
Flow Cytometry – Quality tested 1,2,4
Separation – Reported in literature 3
Recommended Dilutions Please refer to product specific Technical Bulletin
RRID AB_2795135
Gene ID
19264 (Mouse)
Gene Symbol
Ptprc (Mouse)
Gene Aliases loc; B220; Cd45; L-CA; Ly-5; T200; CD45R; Lyt-4
Uniprot ID
P06800 (Mouse)
Uniprot Name
PTPRC_MOUSE 
  • Rat Anti-Mouse CD45RB-PE
    BALB/c mouse splenocytes were stained with Rat Anti-Mouse CD45RB-PE (SB Cat. No. 1675-09).

BALB/c mouse splenocytes were stained with Rat Anti-Mouse CD45RB-PE (SB Cat. No. 1675-09).
 
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References
1. Johnson P, Greenbaum L, Bottomly K, Trowbridge IS. Identification of the alternatively spliced exons of murine CD45 (T200) required for reactivity with B220 and other T200-restricted antibodies. J Exp Med. 1989;169:1179-84. (FC)
2. Hathcock KS, Laszlo G, Dickler HB, Sharrow SO, Johnson P, Trowbridge IS, et al. Expression of variable exon A-, B-, and C-specific CD45 determinants on peripheral and thymic T cell populations. J Immunol. 1992;148:19-28. (FC)
3. Farber DL, Acuto O, Bottomly K. Differential T cell receptor-mediated signaling in naive and memory CD4 T cells. Eur J Immunol. 1997;27:2094-101. (Sep)
4. Borlado LR, Redondo C, Alvarez B, Jimenez C, Criado LM, Flores J, et al. Increased phosphoinositide 3-kinase activity induces a lymphoproliferative disorder and contributes to tumor generation in vivo. FASEB J. 2000;14:895-903. (FC)