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Rat Anti-Mouse BP-1-UNLB
Cat. No.
1770-01
Size
0.5 mg
Price (USD)
$192.00
Qty
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Clone
FG35.4
Isotype
Rat IgG
1
κ
Isotype Control
Rat IgG
1
-UNLB
Specificity
Mouse BP-1
Alternalte Name(s)
Ly-51, 6C3, aminopeptidase A, glutamyl aminopeptidase
Description
BP-1, also known as Ly-51 and 6C3 antigen, is a type II homodimeric transmembrane glycoprotein formed by two disulfide-linked chains of 140 kDa. Originally identified on the surface of pre-B cell lymphomas the cDNA encoding BP-1 has been cloned and found to represent aminopeptidase A. It is expressed at high levels on bone marrow stromal cell lines which support
in vitro
B lymphopoiesis and on a wide variety of mouse tissues known to possess aminopeptidase activity. Subsets of normal bone marrow pre-B and B cells express low levels of BP-1 which is rapidly upregulated on pre-B cells in the presence of IL-7. The BP-1 marker is commonly used to identify B cells in different stages of development.
Format/Conjugate
UNLB (Unconjugated)
Buffer Formulation
Borate buffered saline, pH 8.2
Concentration
0.5 mg/mL
Volume
1.0 mL
Storage & Handling
2-8°C
Please refer to product specific
SDS
Applications
Applications for relevant formats of this clone include -
Flow Cytometry – Quality tested
1
Recommended Dilutions
Please refer to product specific
Technical Bulletin
RRID
AB_2795263
Gene ID
13809
(Mouse)
Gene Symbol
Enpep
(Mouse)
Gene Aliases
APA; Ly51; Ly-51; Bp-1/6C3; 6030431M22Rik
Uniprot ID
P16406
(Mouse)
Uniprot Name
AMPE_MOUSE
Click to Enlarge
Mouse pre-B cell line 18-81 was stained with Rat Anti-Mouse BP-1-PE (SB Cat. No. 1770-09L).
Mouse pre-B cell line 18-81 was stained with Rat Anti-Mouse BP-1-PE (SB Cat. No. 1770-09L).
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References
1.
Welner R, Swett DJ, Pelsue SC. Age-related loss of bone marrow pre-B- and immature B-lymphocytes in the autoimmune-prone flaky skin mutant mice. Autoimmunity. 2005;38:399-408. (FC)
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