Mouse Anti-Human IL-31-UNLB

Cat. No.
15630-01  
Size
0.1 mg  
Price (USD)
$180.00 
Clone SB118b
Isotype Mouse (BALB/c) IgG2bκ
Isotype Control Mouse IgG2b-UNLB
Immunogen E. coli-expressed human IL-31
Specificity Human IL-31
Alternalte Name(s) Interleukin-31
Description Interleukin-31 (IL-31) is a 24 kDa α-helical protein and a member of the IL-6 family of cytokines that is preferentially expressed by CD4+ T cells. This cytokine elicits its response by binding to a heterodimeric complex consisting of a gp130-like receptor chain and the oncostatin M receptor subunit. On target cells which include a broad range of immune and non-immune cells, IL-31 binding can induce activation of the Jak/STAT, AKT, and MAPK signaling pathways. Due to the ubiquitous expression of its receptor complex, IL-31 has numerous physiological roles that include regulating hematopoiesis and immune response. Over-expression has been linked to chronic inflammatory states such as dermatitis, pruritus, airway hypersensitivity, and inflammatory bowel disease.
Format/Conjugate UNLB (Unconjugated)
Buffer Formulation Borate buffered saline, pH 8.2
Concentration 1.0 mg/mL
Volume 0.1 mL
Storage & Handling 2-8°C
Please refer to product specific SDS
Applications
Applications for relevant formats of this clone include -
ELISA – Quality tested
Recommended Dilutions Please refer to product specific Technical Bulletin
RRID AB_2794926
Gene ID
386653 (Human)
Gene Symbol
IL31 (Human)
Gene Aliases IL-31
Uniprot ID
Q6EBC2 (Human)
Uniprot Name
  • Standard curve generated with Mouse Anti-Human IL-31-UNLB and Mouse Anti-Human IL-31-BIOT (SB Cat. No. 15630-08; Clone SB118b) followed by Mouse Anti-BIOT-HRP (SB Cat. No. 6404-05)

Standard curve generated with Mouse Anti-Human IL-31-UNLB and Mouse Anti-Human IL-31-BIOT (SB Cat. No. 15630-08; Clone SB118b) followed by Mouse Anti-BIOT-HRP (SB Cat. No. 6404-05)
 
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