Bovine Type III Collagen-Solution
Cat. No.
1240-02S
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Size
0.5 mg
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Price (USD)
$175.00
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Description |
Collagen is the main structural protein in the extracellular space and is the most abundant protein in the ECM. Collagens are divided into two classes - fibril (types I, II, III, V) and non-fibril (types IV, VI). Type III collagen is expressed in the skin and a variety of internal organs including the lungs, intestinal walls, uterus, and walls of blood vessels and is often associated with type I collagen. It also interacts with platelets in the blood clotting cascade. Type III collagen mutations are associated in a range of diseases including the vascular form of Ehlers–Danlos syndrome. Type III collagen is formed by homotrimers of α1(III) chains.
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Source |
Placental villi
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Purity |
> 90% by SDS-PAGE
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Purification |
Controlled and limited pepsin digestion followed by selective salt precipitation
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Alternalte Name(s) |
COL3A1
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Buffer Formulation |
500 mM acetic acid
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Concentration |
0.5 mg/mL
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Volume |
1.0 mL
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Storage & Handling |
2-8°C
Please refer to product specific SDS
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Applications |
SDS-PAGE – Quality tested ELISA – Reported in literature 1 Surface Plasmon Resonance – Reported in literature 2 In vivo Assays – Reported in literature 4 Coating Material for – Adhesion Studies – Reported in literature 2 Differentiation Studies – Reported in literature 3
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Recommended Dilutions |
Please refer to product specific Technical Bulletin
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References
1. | Stalling SS, Nicoll SB. Fetal ACL fibroblasts exhibit enhanced cellular properties compared with adults. Clin Orthop Relat Res. 2008;466:3130-7. (ELISA, Standard Curve) | 2. | House-Pompeo K, Boles JO, Höök M. Characterization of bacterial adhesin interactions with extracellular matrix components utilizing biosensor technology. Methods. 1994;6:134-42. (SPR, Coating, Adhesion Studies) | 3. | Santiago JA, Pogemiller R, Ogle BM. Heterogeneous differentiation of human mesenchymal stem cells in response to extended culture in extracellular matrices. Tissue Eng Part A. 2009;15:3911-22. (Coating, Differentiation Studies) | 4. | Zhang ZY, Lee CS, Lider O, Weiner HL. Suppression of adjuvant arthritis in Lewis rats by oral administration of type II collagen. J Immunol. 1990;145:2489-93. (In vivo Assays) |
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