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Bovine Type III Collagen-Solution
Cat. No.:
1240-02S
Purified Bovine Type III Collagen solution for use as a coating material and standard.
$203.00
| Description | Collagen is the main structural protein in the extracellular space and is the most abundant protein in the ECM. Collagens are divided into two classes - fibril (types I, II, III, V) and non-fibril (types IV, VI). Type III collagen is expressed in the skin and a variety of internal organs including the lungs, intestinal walls, uterus, and walls of blood vessels and is often associated with type I collagen. It also interacts with platelets in the blood clotting cascade. Type III collagen mutations are associated in a range of diseases including the vascular form of Ehlers–Danlos syndrome. Type III collagen is formed by homotrimers of α1(III) chains. |
|---|---|
| Source | Placental villi |
| Purity | > 90% by SDS-PAGE |
| Purification Method | Controlled and limited pepsin digestion followed by selective salt precipitation |
| Buffer Formulation | 500 mM acetic acid |
| Concentration | 0.5 mg/mL |
| Volume | 1.0 mL |
| Recommended Storage | 2-8°C |
| Applications |
SDS-PAGE – Quality tested ELISA – Reported in literature 1 Surface Plasmon Resonance – Reported in literature 2 In vivo Assays – Reported in literature 4 Coating Material for – Adhesion Studies – Reported in literature 2 Differentiation Studies – Reported in literature 3 |
Documentation
Certificate of Analysis Lookup
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- 1. Stalling SS, Nicoll SB. Fetal ACL fibroblasts exhibit enhanced cellular properties compared with adults. Clin Orthop Relat Res. 2008;466:3130-7. (ELISA, Standard Curve)
- 2. House-Pompeo K, Boles JO, Höök M. Characterization of bacterial adhesin interactions with extracellular matrix components utilizing biosensor technology. Methods. 1994;6:134-42. (SPR, Coating, Adhesion Studies)
- 3. Santiago JA, Pogemiller R, Ogle BM. Heterogeneous differentiation of human mesenchymal stem cells in response to extended culture in extracellular matrices. Tissue Eng Part A. 2009;15:3911-22. (Coating, Differentiation Studies)
- 4. Zhang ZY, Lee CS, Lider O, Weiner HL. Suppression of adjuvant arthritis in Lewis rats by oral administration of type II collagen. J Immunol. 1990;145:2489-93. (In vivo Assays)
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