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Mouse Anti-Human CD55-UNLB (143-30)

Cat. No.:
Purified Anti-Human CD55 antibody for use in flow cytometry, immunohistochemistry, western blot, and immunoprecipitation assays.
Size Price (USD) Quantity
0.1 mg $108.00
More Information
Clone 143-30
Isotype Mouse IgG1κ
Isotype Control Mouse IgG1-UNLB (15H6)
Specificity Human CD55
Alternative Names DAF, decay accelerating factor
Description CD55, also known as decay accelerating factor (DAF), is an 80 kDa GPI-anchored single chain glycoprotein that is expressed on all cells in contact with serum including all hematopoietic cells and the vascular endothelium. A soluble form of CD55 is present in plasma and body fluids. CD55 is a member of the regulator of complement activity (RCA) family of proteins and is thought to play a role in the protection of cells from damage by autologous complement by preventing the amplification steps of the complement cascade. CD55 expression increases upon T cell activation and antibodies to CD55 are mitogenic in the presence of phorbol esters.
Immunogen PHA activated peripheral blood mononuclear cells
Conjugate UNLB (Unconjugated)
Buffer Formulation Borate buffered saline, pH 8.2
Clonality Monoclonal
Concentration 0.1 mg/mL
Volume 1.0 mL
Recommended Storage 2-8°C
Applications Flow Cytometry – Quality tested 5,6
Immunohistochemistry-Frozen Sections – Reported in literature 1
Immunohistochemistry-Paraffin Sections – Reported in literature 2
Immunoprecipitation – Reported in literature 3
Western Blot-Non-Reducing – Reported in literature 4

RRID Number AB_2797046
Gene ID 1604 (Human)
Gene ID Symbol CD55 (Human)
UniProt ID P08174 (Human)
UniProt Name DAF_HUMAN (Human)

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  1. 1. Koretz K, Brüderlein S, Henne C, Möller P. Decay-accelerating factor (DAF, CD55) in normal colorectal mucosa, adenomas and carcinomas. Br J Cancer. 1992;66:810-4. (IHC-FS)
  2. 2. Wu J, Lei L, Wang S, Gu D, Zhang J. Immunohistochemical expression and prognostic value of CD97 and its ligand CD55 in primary gallbladder carcinoma. J Biomed Biotechnol. 2012;2012:587672. (IHC-PS)
  3. 3. Stefanová I, Hořejší V, Ansotegui IJ, Knapp W, Stockinger H. GPI-anchored cell-surface molecules complexed to protein tyrosine kinases. Science. 1991;254:1016-9. (IP)
  4. 4. Clayton A, Harris CL, Court J, Mason MD, Morgan BP. Antigen-presenting cell exosomes are protected from complement-mediated lysis by expression of CD55 and CD59. Eur J Immunol. 2003;33:522-31. (WB)
  5. 5. Zeuke S, Ulmer A, Kusumoto S, Katus HA, Heine H. TLR4-mediated inflammatory activation of human coronary artery endothelial cells by LPS. Cardiovasc Res. 2002;56:126-34. (FC)
  6. 6. Haas P, Aggermann T, Nagl M, Steindl-Kuscher K, Krugluger W, Binder S. Implication of CD21, CD35, and CD55 in the pathogenesis of age-related macular degeneration. Am J Ophthalmol. 2011;152:396-9. (FC)
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