Ensuring timely antibody delivery in the face of supply chain challenges - contact us for solutions

Mouse Anti-Human CD56-BIOT (MEM 188)

Cat. No.:
9456-08
Biotin Anti-Human CD56 antibody for use in flow cytometry, immunohistochemistry / immunocytochemistry, and separation assays.
$196.00
Size Price (USD) Quantity
100 tests $196.00
More Information
Clone MEM 188
Isotype Mouse IgG2aκ
Isotype Control Mouse IgG2a-BIOT (HOPC-1)
Specificity Human/Porcine CD56
Alternative Names NCAM, neural cell adhesion molecule, Leu-19, NKH1
Description CD56, an isoform of the neural cell adhesion molecule (NCAM), is a heavily glycosylated type I transmembrane protein. On human hematopoietic cells its expression is restricted to NK cells and a subpopulation of T lymphocytes (known as large granular lymphocytes) which demonstrate natural killer activity. While it is clear that NCAM plays a role in homotypic adhesion of neuronal cells, the significance of CD56 expression on NK cells is not clear and remains controversial.
Immunogen Acute myelogenous leukemia cell line KG-1
Conjugate BIOT (Biotin)
Buffer Formulation Phosphate buffered saline containing < 0.1% sodium azide
Clonality Monoclonal
Concentration Lot specific
Volume 1.0 mL
Recommended Storage 2-8°C
Applications Flow Cytometry – Quality tested 1,6-9
Immunohistochemistry-Frozen Sections – Reported in literature 1
Immunocytochemistry – Reported in literature 2
Separation – Reported in literature 3,4
Blocking – Reported in literature 5

RRID Number AB_2796804
Gene ID 4684 (Human)
100515564 (Porcine)
Gene ID Symbol NCAM1 (Human)
NCAM1 (Porcine)
Gene ID Aliases CD56; MSK39; NCAM
UniProt ID P13591 (Human)
UniProt Name NCAM1_HUMAN (Human)

Certificate of Analysis Lookup

Enter the Catalog Number and Lot Number for the Certificate of Analysis you wish to view


Need help with this product?
or call 800.722.2255
  1. 1. Zahn S, Rehkämper C, Ferring-Schmitt S, Bieber T, Tüting T, Wenzel J. Interferon-α stimulates TRAIL expression in human keratinocytes and peripheral blood mononuclear cells: implications for the pathogenesis of cutaneous lupus erythematosus. Br J Dermatol. 2011;165:1118-23. (IHC-FS, FC)
  2. 2. Hanabuchi S, Watanabe N, Wang Y, Wang Y, Ito T, Shaw J, et al. Human plasmacytoid predendritic cells activate NK cells through glucocorticoid-induced tumor necrosis factor receptor-ligand (GITRL). Blood. 2006;107:3617-23. (ICC)
  3. 3. Berney SM, Schaan T, Alexander JS, Peterman G, Hoffman PA, Wolf RE, et al. ICAM-3 (CD50) cross-linking augments signaling in CD3-activated peripheral human T lymphocytes. J Leukoc Biol. 1999;65:867-74. (Sep)
  4. 4. Liao, J, Huang M, Fast K, Gundling K, Yadav M, van Brocklyn JR, et al. Immunosuppressive human anti-lymphocyte autoantibodies specific for the type 1 sphingosine 1-phosphate receptor. FASEB J. 2009;23:1786-96. (Sep)
  5. 5. Kos FJ, Chin CS. Costimulation of T cell receptor-triggered IL-2 production by Jurkat T cells via fibroblast growth factor receptor 1 upon its engagement by CD56. Immunol Cell Biol. 2002;80:364-9. (Block)
  6. 6. Hanna J, Mussaffi H, Steuer G, Hanna S, Deeb M, Blau H, et al. Functional aberrant expression of CCR2 receptor on chronically activated NK cells in patients with TAP-2 deficiency. Blood. 2005;106:3465-73. (FC)
  7. 7. Olsen I, Tollefsen S, Aagaard C, Reitan LJ, Bannantine JP, Andersen P, et al. Isolation of Mycobacterium avium subspecies paratuberculosis reactive CD4 T cells from intestinal biopsies of Crohn's disease patients. PLoS One. 2009;4(5):e5641. (FC)
  8. 8. Dimova T, Mihaylova A, Spassova P, Georgieva R. Superficial implantation in pigs is associated with decreased numbers and redistribution of endometrial NK-cell populations. Am J Reprod Immunol. 2008;59:359-69. (FC, Porcine Reactivity)
  9. 9. Wilschut KJ, Jaksani S, Van Den Dolder J, Haagsman HP, Roelen BA. Isolation and characterization of porcine adult muscle-derived progenitor cells. J Cell Biochem. 2008;105:1228-39. (FC, Porcine Reactivity)
See All References