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Mouse Anti-Human GFAP-UNLB (SB61b)

Cat. No:
12075-01
Purified Anti-Human GFAP antibody for use in ELISA, immunohistochemistry / immunocytochemistry, and western blot assays.
$200.00
Size Price (USD) Quantity
0.5 mg $200.00
More Information
Clone SB61b
Isotype Mouse (BALB/c) IgG2bκ
Isotype Control Mouse IgG2b-UNLB (A-1)
Specificity Human/Mouse GFAP
Alternative Names Glial fibrillary acidic protein, intermediate filament protein
Description Glial fibrillary acid protein (GFAP) is a member of the type III intermediate filament family of proteins. GFAP is heavily expressed in astrocytes and certain other astroglia in the central nervous system, in satellite cells in peripheral ganglia, and in non-myelinating Schwann cells in peripheral nerves. It is closely related to its non-epithelial family members, vimentin, desmin, and peripherin, which are all involved in the structure and functions of the cell’s cytoskeleton. GFAP is thought to help to maintain astrocyte mechanical strength, as well as the shape of cell; however, its precise function remains poorly understood. In adults, GFAP levels increase in response to the proliferation of astrocytes associated with Alzheimer’s disease, epilepsy, and multiple sclerosis. Antibodies specific for GFAP are useful as markers of astrocytic cells and neural stem cells as well as for distinguishing neoplasms of astrocytic origin from other neoplasms in the central nervous system.
Immunogen Recombinant human GFAP
Conjugate UNLB (Unconjugated)
Buffer Formulation Borate buffered saline, pH 8.2
Clonality Monoclonal
Concentration 0.5 mg/mL
Volume 1.0 mL
Recommended Storage 2-8°C
Applications Immunocytochemistry – Quality tested
Immunohistochemistry-Frozen Sections – Reported in literature 1
Western Blot 2
ELISA-Detection 2

Note – May be paired with the purified clone SB61a (SB Cat. No. 12070-01) in a sandwich ELISA

RRID Number AB_2794711
Gene ID 2670 (Human)
14580 (Mouse)
Gene ID Symbol GFAP (Human)
Gfap (Mouse)
Gene ID Aliases ALXDRD; AI836096
UniProt ID P14136 (Human)
P03995 (Mouse)
UniProt Name GFAP_HUMAN (Human)
GFAP_MOUSE (Mouse)

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  1. 1. Pons-Espinal M, de Lagran MM, Dierssen M. Environmental enrichment rescues DYRK1A activity and hippocampal adult neurogenesis in TgDyrk1A. Neurobiol Dis. 2013;60:18-31. (IHC-FS, Mouse Reactivity)
  2. 2. SouthernBiotech unpublished data (WB, ELISA)