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Mouse Anti-Human IL-31-UNLB (SB118b)

Cat. No.:
15630-01
Purified Anti-Human IL-31 antibody for use in ELISA assays.
$180.00
Size Price (USD) Quantity
0.1 mg $180.00
More Information
Clone SB118b
Isotype Mouse (BALB/c) IgG2bκ
Isotype Control Mouse IgG2b-UNLB (A-1)
Specificity Human IL-31
Alternative Names Interleukin-31
Description Interleukin-31 (IL-31) is a 24 kDa α-helical protein and a member of the IL-6 family of cytokines that is preferentially expressed by CD4+ T cells. This cytokine elicits its response by binding to a heterodimeric complex consisting of a gp130-like receptor chain and the oncostatin M receptor subunit. On target cells which include a broad range of immune and non-immune cells, IL-31 binding can induce activation of the Jak/STAT, AKT, and MAPK signaling pathways. Due to the ubiquitous expression of its receptor complex, IL-31 has numerous physiological roles that include regulating hematopoiesis and immune response. Over-expression has been linked to chronic inflammatory states such as dermatitis, pruritus, airway hypersensitivity, and inflammatory bowel disease.
Immunogen E. coli-expressed human IL-31
Conjugate UNLB (Unconjugated)
Buffer Formulation Borate buffered saline, pH 8.2
Clonality Monoclonal
Concentration 1.0 mg/mL
Volume 0.1 mL
Recommended Storage 2-8°C
Applications ELISA – Quality tested

RRID Number AB_2794926
Gene ID 386653 (Human)
Gene ID Symbol IL31 (Human)
Gene ID Aliases IL-31
UniProt ID Q6EBC2 (Human)
UniProt Name IL31_HUMAN (Human)

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