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Mouse Anti-Human TIMP-4-UNLB (SB30c)

Cat. No.:
12035-01
Purified Anti-Human TIMP-4 antibody for use in immunohistochemistry / immunocytochemistry, ELISA, and western blotting assays.
$205.00
Size Price (USD) Quantity
0.1 mg $205.00
More Information
Clone SB30c
Isotype Mouse (BALB/c) IgG2aκ
Isotype Control Mouse IgG2a-UNLB (HOPC-1)
Specificity Human/Mouse/Rat TIMP-4
Alternative Names Tissue inhibitor of metalloproteinase 4
Description Tissue inhibitors of matrix metalloproteinases (TIMPs) constitute a family of secreted multifunctional proteins which are classified based on structural similarity to each other as well as their ability to inhibit matrix metalloproteinases (MMPs). TIMPs play a critical role in ECM homeostasis but have also been shown to have erythroid-potentiating and cell growth-promoting activities. TIMP-4, unlike TIMP-1, TIMP-2 and TIMP-3, shows restricted localization to cardiac, neural, breast, and muscle tissue. Cardiospecific TIMP-4 seems to play a significant role in regulating the normal cell phenotype since reduced levels elicit cellular transformation.
Immunogen Recombinant human TIMP-4 (a.a. 35-224)
Conjugate UNLB (Unconjugated)
Buffer Formulation Borate buffered saline, pH 8.2
Clonality Monoclonal
Concentration 0.5 mg/mL
Volume 0.2 mL
Recommended Storage 2-8°C
Applications Western Blot – Quality tested 1-3
Immunohistochemistry-Paraffin Sections 4
Immunocytochemistry 4
ELISA 5

RRID Number AB_2794707
Gene ID 7079 (Human)
110595 (Mouse)
680130 (Rat)
Gene ID Symbol TIMP4 (Human)
Timp4 (Mouse)
Timp4 (Rat)
Gene ID Aliases TIMP-4; Timp-4
UniProt ID Q99727 (Human)
Q9JHB3 (Mouse)
P81556 (Rat)
UniProt Name TIMP4_HUMAN (Human)
TIMP4_MOUSE (Mouse)
TIMP4_RAT (Rat)

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  1. 1. Alarab M, Kufaishi H, Lye S, Drutz H, Shynlova O. Expression of extracellular matrix-remodeling proteins is altered in vaginal tissue of premenopausal women with severe pelvic organ prolapse. Reprod Sci. 2014;21:704-15. (WB)
  2. 2. Zambirinis CP, Levie E, Nguy S, Avanzi A, Barilla R, Xu Y, et al. TLR9 ligation in pancreatic stellate cells promotes tumorigenesis. J Exp Med. 2015;212:2077-94. (WB, Mouse Reactivity)
  3. 3. Ketsawatsomkron P, Keen HL, Davis DR, Lu K, Stump M, De Silva TM, et al. Protective role for tissue inhibitor of metalloproteinase-4, a novel peroxisome proliferator-activated receptor-γ target gene, in smooth muscle in deoxycorticosterone acetate-salt hypertension. Hypertension. 2016;67:214-22. (WB, Mouse & Rat Reactivity)
  4. 4. SouthernBiotech published data (IHC-PS, ICC)
  5. 5. SouthernBiotech unpublished data (ELISA)
See All References