Collagens are the most abundant protein in the extracellular matrix (ECM). Collagens are involved in cell adhesion and aid in maintaining tissue architecture and function. They are the main structural protein in the extracellular space, are major components of connective tissues (tendons, cartilage, ligaments, and skin), and are found in bone, intervertebral discs, corneas, blood vessels, tooth dentin, and gut tissue.
Collagen types I, II, III, IV, and V are the most common with type I being the most predominant. Types I, II, III, and V are fibril forming collagens while types IV and VI are non-fibral collagens forming the basal lamina. For over three decades SouthernBiotech has provided polyclonal and monoclonal anti-collagen antibodies for use in western blot, ELISA, and immunohistochemistry assays for your matrix biology research.