Rat Anti-Mouse BP-1-BIOT

Cat. No.
1770-08  
Size
0.5 mg   		Price (USD)
$225.00 
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Clone FG35.4
Isotype Rat IgG1κ
Isotype Control Rat IgG1-BIOT
Specificity Mouse BP-1
Alternalte Name(s) Ly-51, 6C3, aminopeptidase A, glutamyl aminopeptidase
Description BP-1, also known as Ly-51 and 6C3 antigen, is a type II homodimeric transmembrane glycoprotein formed by two disulfide-linked chains of 140 kDa. Originally identified on the surface of pre-B cell lymphomas the cDNA encoding BP-1 has been cloned and found to represent aminopeptidase A. It is expressed at high levels on bone marrow stromal cell lines which support in vitro B lymphopoiesis and on a wide variety of mouse tissues known to possess aminopeptidase activity. Subsets of normal bone marrow pre-B and B cells express low levels of BP-1 which is rapidly upregulated on pre-B cells in the presence of IL-7. The BP-1 marker is commonly used to identify B cells in different stages of development.
Format/Conjugate BIOT (Biotin)
Buffer Formulation Phosphate buffered saline containing 0.1% sodium azide
Concentration 0.5 mg/mL
Volume 1.0 mL
Storage & Handling 2-8°C
Please refer to product specific SDS
Applications
Applications for relevant formats of this clone include -
Flow Cytometry – Quality tested 1
Recommended Dilutions Please refer to product specific Technical Bulletin
RRID AB_2795265
Gene ID
13809 (Mouse)
Gene Symbol
Enpep (Mouse)
Gene Aliases APA; Ly51; Ly-51; Bp-1/6C3; 6030431M22Rik
Uniprot ID
P16406 (Mouse)
Uniprot Name
AMPE_MOUSE 
  • Rat Anti-Mouse BP-1-PE
    Mouse pre-B cell line 18-81 was stained with Rat Anti-Mouse BP-1-PE (SB Cat. No. 1770-09L).

Mouse pre-B cell line 18-81 was stained with Rat Anti-Mouse BP-1-PE (SB Cat. No. 1770-09L).
 
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References
1. Welner R, Swett DJ, Pelsue SC. Age-related loss of bone marrow pre-B- and immature B-lymphocytes in the autoimmune-prone flaky skin mutant mice. Autoimmunity. 2005;38:399-408. (FC)