Mouse Anti-Mouse Ly-49I-FITC

Cat. No.
1802-02  
Size
0.5 mg   		Price (USD)
$255.00 
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Clone YLI-90
Isotype Mouse (BALB/c) IgG1κ
Isotype Control Mouse IgG1-FITC
Immunogen CHO-K1 cells transfected with B6 allele of Ly49I gene
Specificity Mouse Ly-49I
Alternalte Name(s) Ly-49
Description The monoclonal antibody YLI-90 reacts with the B6 allele of Ly49I, a member of the lectin-like homodimeric Ly49 family of cell surface receptors. Mouse Ly49 receptors exhibit allelic specificity for MHC class I Ia molecules and are thought to serve to prevent natural killer (NK) cells from attacking normal cells while allowing them to attack infected or transformed cells in which class I molecules have been down-regulated. These inhibitory receptors are also expressed on subpopulations of mouse CD8+ T cells. The YLI-90 antibody stains ~45% of NK1.1+CD3- splenocytes from C57BL/6 mice.
Format/Conjugate FITC (Fluorescein)
Buffer Formulation Phosphate buffered saline containing 0.1% sodium azide
Concentration 0.5 mg/mL
Volume 1.0 mL
Storage & Handling 2-8°C; Avoid exposure to light
Please refer to product specific SDS
Applications
Applications for relevant formats of this clone include -
Flow Cytometry – Quality tested 1,2
Recommended Dilutions Please refer to product specific Technical Bulletin
RRID AB_2795332
Gene ID
16640 (Mouse)
Gene Symbol
Klra9 (Mouse)
Gene Aliases LY49I1; Ly49I
  • Mouse Anti-Mouse Ly-49I-BIOT
    C57BL/6 mouse splenocytes were stained with Mouse Anti-Mouse Ly-49I-BIOT (SB Cat. 1802-08) and Mouse Anti-Mouse NK1.1-PE (SB Cat. No. 1805-09) followed by Streptavidin-FITC (SB Cat. No. 7100-02).

C57BL/6 mouse splenocytes were stained with Mouse Anti-Mouse Ly-49I-BIOT (SB Cat. 1802-08) and Mouse Anti-Mouse NK1.1-PE (SB Cat. No. 1805-09) followed by Streptavidin-FITC (SB Cat. No. 7100-02).
 
Related Products (4)
References
1. Coles MC, McMahon CW, Takizawa H, Raulet DH. Memory CD8 T lymphocytes express inhibitory MHC-specific Ly49 receptors. Eur J Immunol. 2000;30:236-44. (Immunogen, FC)
2. Corral L, Takizawa H, Hanke T, Jamieson AM, Raulet DH. A new monoclonal antibody reactive with several Ly49 NK cell receptors mediates redirected lysis of target cells. Hybridoma. 1999;18:359-66. (FC)