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Mouse Anti-Mouse Ly-49I-PE (YLI-90)

Cat. No.:
PE Anti-Mouse Ly-49I antibody for use in flow cytometry assays.
Size Price (USD) Quantity
0.1 mg $193.00
More Information
Clone YLI-90
Isotype Mouse (BALB/c) IgG1κ
Isotype Control Mouse IgG1-PE (15H6)
Specificity Mouse Ly-49I
Alternative Names Ly-49
Description The monoclonal antibody YLI-90 reacts with the B6 allele of Ly49I, a member of the lectin-like homodimeric Ly49 family of cell surface receptors. Mouse Ly49 receptors exhibit allelic specificity for MHC class I Ia molecules and are thought to serve to prevent natural killer (NK) cells from attacking normal cells while allowing them to attack infected or transformed cells in which class I molecules have been down-regulated. These inhibitory receptors are also expressed on subpopulations of mouse CD8+ T cells. The YLI-90 antibody stains ~45% of NK1.1+CD3- splenocytes from C57BL/6 mice.
Immunogen CHO-K1 cells transfected with B6 allele of Ly49I gene
Conjugate PE (R-phycoerythrin)
Buffer Formulation Phosphate buffered saline containing < 0.1% sodium azide and a stabilizer
Clonality Monoclonal
Concentration 0.1 mg/mL
Volume 1.0 mL
Recommended Storage 2-8°C; Avoid exposure to light; Do not freeze
Applications Flow Cytometry – Quality tested 1,2

RRID Number AB_2795334
Gene ID 16640 (Mouse)
Gene ID Symbol Klra9 (Mouse)
Gene ID Aliases LY49I1; Ly49I

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  1. 1. Coles MC, McMahon CW, Takizawa H, Raulet DH. Memory CD8 T lymphocytes express inhibitory MHC-specific Ly49 receptors. Eur J Immunol. 2000;30:236-44. (Immunogen, FC)
  2. 2. Corral L, Takizawa H, Hanke T, Jamieson AM, Raulet DH. A new monoclonal antibody reactive with several Ly49 NK cell receptors mediates redirected lysis of target cells. Hybridoma. 1999;18:359-66. (FC)