Mouse Anti-Mouse Ly-49I-PE

Cat. No.
1802-09  
Size
0.1 mg  
Price (USD)
$175.00 
Clone YLI-90
Isotype Mouse (BALB/c) IgG1κ
Isotype Control Mouse IgG1-PE
Immunogen CHO-K1 cells transfected with B6 allele of Ly49I gene
Specificity Mouse Ly-49I
Alternalte Name(s) Ly-49
Description The monoclonal antibody YLI-90 reacts with the B6 allele of Ly49I, a member of the lectin-like homodimeric Ly49 family of cell surface receptors. Mouse Ly49 receptors exhibit allelic specificity for MHC class I Ia molecules and are thought to serve to prevent natural killer (NK) cells from attacking normal cells while allowing them to attack infected or transformed cells in which class I molecules have been down-regulated. These inhibitory receptors are also expressed on subpopulations of mouse CD8+ T cells. The YLI-90 antibody stains ~45% of NK1.1+CD3- splenocytes from C57BL/6 mice.
Format/Conjugate PE (R-phycoerythrin)
Buffer Formulation Phosphate buffered saline containing 0.1% sodium azide and a stabilizer
Concentration 0.1 mg/mL
Volume 1.0 mL
Storage & Handling 2-8°C; Avoid exposure to light; Do not freeze
Please refer to product specific SDS
Applications
Applications for relevant formats of this clone include -
Flow Cytometry – Quality tested 1,2
Recommended Dilutions Please refer to product specific Technical Bulletin
RRID AB_2795334
Gene ID
16640 (Mouse)
Gene Symbol
Klra9 (Mouse)
Gene Aliases LY49I1; Ly49I
  • C57BL/6 mouse splenocytes were stained with Mouse Anti-Mouse Ly-49I-PE (SB Cat. No. 1802-09) and Mouse Anti-Mouse NK1.1-FITC (SB Cat. No. 1805-02).

C57BL/6 mouse splenocytes were stained with Mouse Anti-Mouse Ly-49I-PE (SB Cat. No. 1802-09) and Mouse Anti-Mouse NK1.1-FITC (SB Cat. No. 1805-02).
 
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References
1. Coles MC, McMahon CW, Takizawa H, Raulet DH. Memory CD8 T lymphocytes express inhibitory MHC-specific Ly49 receptors. Eur J Immunol. 2000;30:236-44. (Immunogen, FC)
2. Corral L, Takizawa H, Hanke T, Jamieson AM, Raulet DH. A new monoclonal antibody reactive with several Ly49 NK cell receptors mediates redirected lysis of target cells. Hybridoma. 1999;18:359-66. (FC)