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Goat Anti-Human IgM-TXRD

Cat. No.:
2020-07
Goat Anti-Human IgM-Texas Red antibody for use in flow cytometry and immunohistochemistry / immunocytochemistry assays.
$99.00
Size Price (USD) Quantity
1.0 mg $99.00
More Information
Isotype Goat IgG
Isotype Control Goat IgG-TXRD
Specificity Reacts with the heavy chain of human IgM
Source Pooled antisera from goats hyperimmunized with human IgM
Cross Adsorption Human IgG and IgA; may react with IgM from other species
Purification Method Affinity chromatography on human IgM covalently linked to agarose
Conjugate TXRD (Texas Red®)
Buffer Formulation Phosphate buffered saline containing < 0.1% sodium azide
Clonality Polyclonal
Concentration 1.0 mg/mL
Volume 1.0 mL
Recommended Storage 2-8°C; Avoid exposure to light
Trademark Information Texas Red® is a registered trademark of Thermo Fisher Scientific, Inc. or its subsidiaries
Applications Quality tested applications for relevant formats include -
ELISA 1-3,15
FLISA
Flow Cytometry 16-18

Other referenced applications for relevant formats include -
ELISpot 2,4,5,11
Immunohistochemistry-Frozen Sections 6,7
Immunohistochemistry-Paraffin Sections 8,9
Immunocytochemistry 8,10,11
Western Blot 12,13
Immunoprecipitation 13-15
Multiplex 19,20
Stimulation 21-23
Purification 24
Depletion 25
RRID Number AB_2795604
Gene ID 3507 (Human)
Gene ID Symbol IGHM (Human)
Gene ID Aliases AGM1; MU; VH
UniProt ID P01871 (Human
UniProt Name IGHM_HUMAN (Human)

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  7. 7. Forshammar J, Isaksson S, Strid H, Stotzer P, Sjövall H, Simrén M, et al. A pilot study of colonic B cell pattern in irritable bowel syndrome. Scand J Gastroenterol. 2008;43:1461-6. (IHC-FS)
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  9. 9. Rowley AH, Shulman ST, Mask CA, Finn LS, Terai M, Baker SC, et al. IgA plasma cell infiltration of proximal respiratory tract, pancreas, kidney, and coronary artery in acute Kawasaki disease. J Infect Dis. 2000;182:1183-91. (IHC-PS)
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  13. 13. Santiago T, Kulemzin SV, Reshetnikova ES, Chikaev NA, Volkova OY, Mechetina LV, et al. FCRLA is a resident endoplasmic reticulum protein that associates with intracellular Igs, IgM, IgG and IgA. Int Immunol. 2011;23:43-53. (IP, WB)
  14. 14. Pollok BA, Anker R, Eldridge P, Hendershot L, Levitt D. Molecular basis of the cell-surface expression of immunoglobulin μ chain without light chain in human B lymphocytes. Proc Natl Acad Sci USA. 1987;84:9199-203. (IP)
  15. 15. Minegishi Y, Conley ME. Negative selection at the pre-BCR checkpoint elicited by human μ heavy chains with unusual CDR3 regions. Immunity. 2001;14:631-41. (ELISA, IP)
  16. 16. Mongini PK, Blessinger C, Posnett DN, Rudich SM. Membrane IgD and membrane IgM differ in capacity to transduce inhibitory signals within the same human B cell clonal populations. J Immunol. 1989;143:1565-74. (FC)
  17. 17. Dobbs AK, Yang T, Farmer D, Kager L, Parolini O, Conley ME. Cutting edge: a hypomorphic mutation in Igβ (CD79b) in a patient with immunodeficiency and a leaky defect in B cell development. J Immunol. 2007;179:2055-9. (FC)
  18. 18. Azimzadeh AM, Byrne GW, Ezzelarab M, Welty E, Braileanu G, Cheng X, et al. Development of a consensus protocol to quantify primate anti-non-Gal xenoreactive antibodies using pig aortic endothelial cells. Xenotransplantation. 2014;21:555-66. (FC)
  19. 19. Tomaras GD, Yates NL, Liu P, Qin L, Fouda GG, Chavez LL, et al. Initial B-cell responses to transmitted human immunodeficiency virus type 1: virion-binding immunoglobulin M (IgM) and IgG antibodies followed by plasma anti-gp41 antibodies with ineffective control of initial viremia. J Virol. 2008;82:12449-63. (Multiplex)
  20. 20. Pochechueva T, Chinarev A, Bovin N, Fedier A, Jacob F, Heinzelmann-Schwarz V. PEGylation of microbead surfaces reduces unspecific antibody binding in glycan-based suspension array. J Immunol Methods. 2014;412:42-52. (Multiplex)
  21. 21. Blaeser F, Ho N, Prywes R, Chatila TA. Ca2+-dependent gene expression mediated by MEF2 transcription factors. J Biol Chem. 2000;275:197-209. (Stim)
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  23. 23. Woyach JA, Bojnik E, Ruppert AS, Stefanovski MR, Goettl VM, Smucker KA, et al. Bruton's tyrosine kinase (BTK) function is important to the development and expansion of chronic lymphocytic leukemia (CLL). Blood. 2014;123:1207-13. (Stim)
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