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Mouse Anti-Chicken ChT1-BIOT (CT1)
Cat. No.:
8410-08
Biotin Anti-Chicken ChT1 antibody for use in flow cytometry and immunoprecipitation assays.
$336.00
| Clone | CT1 |
|---|---|
| Isotype | Mouse IgG1κ |
| Isotype Control | Mouse IgG1-BIOT (15H6) |
| Specificity | Chicken/Quail ChT1 |
| Alternative Names | Chicken thymocyte receptor, chicken T cell thymocyte Ag 1 |
| Description | ChT1, a member of the Ig superfamily with one V-like and one C2-like domain, is a T cell antigen that is expressed on the surface of embryonic thymocytes (day 10). In young chickens about 90% of the thymocytes as well as a subpopulation of peripheral lymphocytes, which represent recent thymic emigrants are ChT1 positive. Expression in the periphery declines with age and, in correlation with partial thymectomy, indicates that ChT1 can be used as an accurate marker for studying thymic function. The monoclonal antibody CT1 also recognizes the ChT1 antigen in quail cortical thymocytes. |
| Immunogen | Chicken thymocytes |
| Conjugate | BIOT (Biotin) |
| Buffer Formulation | Phosphate buffered saline containing < 0.1% sodium azide |
| Clonality | Monoclonal |
| Concentration | 0.5 mg/mL |
| Volume | 1.0 mL |
| Recommended Storage | 2-8°C |
| Applications |
Flow Cytometry – Quality tested 1-4 Immunoprecipitation – Reported in literature 1 |
| RRID Number | AB_2796561 |
| Gene ID |
414795 (Chicken) 107312786 (Quail) |
| Gene ID Symbol |
VSIG1 (Chicken) VSIG1 (Quail) |
| Gene ID Aliases | CHT1 |
| UniProt ID |
Q9PWR4 (Chicken) |
| UniProt Name |
VSIG1_CHICK (Chicken) |
Documentation
Certificate of Analysis Lookup
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- 1. Chen CH, Chanh TC, Cooper MD. Chicken thymocyte-specific antigen identified by monoclonal antibodies: ontogeny, tissue distribution and biochemical characterization. Eur J Immunol. 1984;14:385-91. (Immunogen, FC, IP, Quail Reactivity)
- 2. Hemendinger RA, Bloom SE. Selective mitomycin C and cyclophosphamide induction of apoptosis in differentiating B lymphocytes compared to T lymphocytes in vivo. Immunopharmacology. 1996;35:71-82. (FC)
- 3. Kong F, Chen CH, Cooper MD. Thymic function can be accurately monitored by the level of recent T cell emigrants in the circulation. Immunity. 1998;8:97-104. (FC)
- 4. Rudrappa SG, Humphrey BD. Energy metabolism in developing chicken lymphocytes is altered during the embryonic to posthatch transition. J Nutr. 2007;137:427-32. (FC)
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