Ensuring timely antibody delivery in the face of supply chain challenges - contact us for solutions

Mouse Anti-Human CD158e1-UNLB (DX9)

Cat. No.:
9850-01
Purified Anti-Human CD158e1 antibody for use in flow cytometry, immunohistochemistry / immunocytochemistry, immunoprecipitation, and blocking assays.
$138.00
Size Price (USD) Quantity
0.1 mg $138.00
More Information
Clone DX9
Isotype Mouse (BALB/c) IgG1κ
Isotype Control Mouse IgG1-UNLB (15H6)
Specificity Human/Baboon CD158e1
Alternative Names NKB1, p70, KIR, 3DL1, KIR3DL1, KIR3D, NKAT3
Description CD158e1 is a 70 kDa transmembrane glycoprotein and a killer cell immunoglobulin (Ig)-like receptor (KIR) that is expressed on a subset of natural killer cells and T cells. The monoclonal antibody DX9 is expressed on a subset of CD3-, CD56+ NK cells isolated from peripheral blood at varying levels (<0.1% to 61%) among individuals but not on thymocytes, b lymphocytes, granulocytes, or monocytes. interactions with cd158e1 and certain mhc hla-b antigens a target cell inhibits cytotoxicity, possibly preventing lysis death. kir class i may regulate nk t response antigen stimulation.
Immunogen Human NK clone VL186-1 (CD3-, CD16+, CD56+)
Conjugate UNLB (Unconjugated)
Buffer Formulation Borate buffered saline, pH 8.2
Clonality Monoclonal
Concentration 0.1 mg/mL
Volume 1.0 mL
Recommended Storage 2-8°C
Applications Flow Cytometry – Quality tested 1,2,4,6-9
Immunohistochemistry-Frozen Sections – Reported in literature 2
Immunohistochemistry-Paraffin Sections – Reported in literature 3
Immunocytochemistry – Reported in literature 4
Immunoprecipitation – Reported in literature 1,4,9
Blocking – Reported in literature 1,5,7-9

RRID Number AB_2797122
Gene ID 3811 (Human)
Gene ID Symbol KIR3DL1 (Human)
Gene ID Aliases KIR; NKB1; NKAT3; NKB1B; NKAT-3; CD158E1; KIR3DL1/S1
UniProt ID P43629 (Human)
UniProt Name KI3L1_HUMAN (Human)

Certificate of Analysis Lookup

Enter the Catalog Number and Lot Number for the Certificate of Analysis you wish to view


Need help with this product?
or call 800.722.2255
  1. 1. Litwin V, Gumperz J, Parham P, Phillips JH, Lanier LL. NKB1: a natural killer cell receptor involved in the recognition of polymorphic HLA-B molecules. J Exp Med. 1994;180:537-43. (Immunogen, Block, FC, IP)
  2. 2. Schleinitz N, Cognet C, Guia S, Laugier-Anfossi F, Baratin M, Pouget J, et al. Expression of the CD85j (leukocyte Ig-like receptor 1, Ig-like transcript 2) receptor for class I major histocompatibility complex molecules in idiopathic inflammatory myopathies. Arthritis Rheum. 2008;58:3216-23. (FC, IHC-FS)
  3. 3. Hisashi Y, Yamada K, Kuwaki K, Tseng Y, Dor FJ, Houser SL, et al. Rejection of cardiac xenografts transplanted from α 1,3-galactosyltransferase gene-knockout (GalT-KO) pigs to baboons. Am J Transplant. 2008;8:2516-26. (IHC-PS, Baboon Reactivity)
  4. 4. Purdy AK, Alvarez Arias DA, Oshinsky J, James AM, Serebriiskii I, Campbell KS. The AP-2 clathrin adaptor mediates endocytosis of an inhibitory killer cell Ig-like receptor in human NK cells. J Immunol. 2014;193:4675-83. (FC, IP, ICC)
  5. 5. Söderström K, Corliss B, Lanier LL, Phillips JH. CD94/NKG2 is the predominant inhibitory receptor involved in recognition of HLA-G by decidual and peripheral blood NK cells. J Immunol. 1997;159:1072-5. (Block)
  6. 6. D'Andrea A, Chang C, Franz-Bacon K, McClanahan T, Phillips JH, Lanier LL. Molecular cloning of NKB1. A natural killer cell receptor for HLA-B allotypes. J Immunol. 1995;155:2306-10. (FC)
  7. 7. Valiante NM, Uhrberg M, Shilling HG, Lienert-Weidenbach K, Arnett KL, D'Andrea A, et al. Functionally and structurally distinct NK cell receptor repertoires in the peripheral blood of two human donors. Immunity. 1997;7:739-51. (FC, Block)
  8. 8. Bakker AB, Phillips JH, Figdor CG, Lanier LL . Killer cell inhibitory receptors for MHC class I molecules regulate lysis of melanoma cells mediated by NK cells, γδ T cells, and antigen-specific CTL. J Immunol. 1998;160:5239-45. (FC, Block)
  9. 9. Yusa S, Catina TL, Campbell KS. SHP-1- and phosphotyrosine-independent inhibitory signaling by a killer cell Ig-like receptor cytoplasmic domain in human NK cells. J Immunol. 2002;168:5047-57. (FC, IP, Block)
See All References