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Mouse Anti-Human CD61-PE (PM6/13)

Cat. No.:
9470-09
PE Anti-Human CD61 antibody for use in flow cytometry assays.
$226.00
Size Price (USD) Quantity
100 tests $226.00
More Information
Clone PM6/13
Isotype Mouse (BALB/c) IgG1κ
Isotype Control Mouse IgG1-PE (15H6)
Specificity Human CD61
Alternative Names Integrin β3, GPIIIa
Description CD61 is the integrin β3 subunit, a 110 kDa transmembrane glycoprotein expressed on platelets, megakaryocytes, and endothelial cells. Integrin β3 associates with gpIIb (CD41) to form the CD41/CD61 complex that mediates platelet adhesion and aggregation. CD61 also associates with CD51 to form the αVβ3 vitronectin receptor.
Immunogen Human platelet plasma membrane
Conjugate PE (R-phycoerythrin)
Buffer Formulation Phosphate buffered saline containing < 0.1% sodium azide and a stabilizer
Clonality Monoclonal
Concentration Lot specific
Volume 1.0 mL
Recommended Storage 2-8°C; Avoid exposure to light; Do not freeze
Applications Flow Cytometry – Quality tested 2,5-7
Immunocytochemistry – Reported in literature 2
Immunoprecipitation – Reported in literature 1
Western Blot-Non-Reducing – Reported in literature 1
Blocking – Reported in literature 1,3,4
Adhesion – Reported in literature 4
ELISA – Reported in literature 3

RRID Number AB_2796814
Gene ID 3690 (Human)
Gene ID Symbol ITGB3 (Human)
Gene ID Aliases BDPLT16; BDPLT2; CD61; GP3A; GPIIIa; GT
UniProt ID P05106 (Human
UniProt Name ITB3_HUMAN (Human)

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  1. 1. Patel Y, Rahman S, Siddiqua A, Wilkinson JM, Kakkar VV, Authi KS. Functional characterization of PM6/13, a β3-specific (GPIIIa/CD61) monoclonal antibody that shows preferential inhibition of fibrinogen binding over fibronectin binding to activated human platelets. Thromb Haemost. 1998;79:177-85. (Immunogen, IP, WB-NR, Block)
  2. 2. Wilkinson JM, Sankar AA, Currie MJ. The expression of adhesion receptors and cytoskeletal proteins in the megakaryoblastic cell line CHRF-288-11. In: Schlossman SF, Boumsell L, Gilks W, Harlan JM, Kishimoto T, Morimoto C, et al, editors. Leukocyte Typing V: White Cell Differentiation Antigens. Oxford: Oxford University Press; 1995. p. 1210-13. (FC, ICC)
  3. 3. Komiya E, Sato H, Watanabe N, Ise M, Higashi S, Miyagi Y, et al. Angiomodulin, a marker of cancer vasculature, is upregulated by vascular endothelial growth factor and increases vascular permeability as a ligand of integrin αvβ3. Cancer Med. 2014;3:537-49. (ELISA, Block)
  4. 4. Gu Y, Nilsson K, Eng H, Ekblom M. Association of extracellular matrix proteins fibulin-1 and fibulin-2 with fibronectin in bone marrow stroma. Br J Haematol. 2000;109:305-13. (Block, Adhesion)
  5. 5. Hapke S, Kessler H, de Prada NA, Benge A, Schmitt M, Lengyel E. Integrin αvβ3/vitronectin interaction affects expression of the urokinase system in human ovarian cancer cells. J Biol Chem. 2001;276:26340-8. (FC)
  6. 6. Lester EA, Babensee JE. Proinflammatory phenotype of endothelial cells after coculture with biomaterial-treated blood cells. J Biomed Mater Res A. 2003;64:397-410. (FC)
  7. 7. Rose SL, Babensee JE. Procoagulant phenotype of endothelial cells after coculture with biomaterial-treated blood cells. J Biomed Mater Res A. 2005;72:269-78. (FC)
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