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Mouse Anti-Chicken IgM-BIOT (M-4)

Cat. No.:
Biotin Anti-Chicken IgM antibody for use in flow cytometry and immunoprecipitation assays.
Size Price (USD) Quantity
0.5 mg $336.00
More Information
Clone M-4
Isotype Mouse (BALB/c) IgMκ
Isotype Control Mouse IgM-BIOT (11E10)
Specificity Chicken/Turkey IgM
Immunogen Affinity purified chicken Ig or isolated lymphocytes
Conjugate BIOT (Biotin)
Buffer Formulation Phosphate buffered saline containing < 0.1% sodium azide
Clonality Monoclonal
Concentration 0.5 mg/mL
Volume 1.0 mL
Recommended Storage 2-8°C
Applications Flow Cytometry – Quality tested 17-21
Immunoprecipitation – Reported in literature 1
Stimulation – Reported in literature 2-17
Apoptosis – Reported in literature 7,8

RRID Number AB_2796487
Gene ID 107050812 (Chicken)
Gene ID Symbol LOC107050812 (Chicken)
UniProt ID P01875 (Chicken)
UniProt Name IGHM_CHICK (Chicken)

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  1. 1. Chen CH, Lehmeyer JE, Cooper MD. Evidence for an IgD homologue on chicken lymphocytes. J Immunol. 1982;129:2580-5. (Immunogen, IP)
  2. 2. Mahajan S, Vassilev A, Sun N, Ozer Z, Mao C, Uckun FM. Transcription factor STAT5A is a substrate of Bruton's tyrosine kinase in B cells. J Biol Chem. 2001;276:31216-28. (Stim)
  3. 3. Venkatachalam K, Ma H, Ford DL, Gill DL. Expression of functional receptor-coupled TRPC3 channels in DT40 triple receptor InsP3 knockout cells. J Biol Chem. 2001;276:33980-5. (Stim)
  4. 4. Patterson RL, van Rossum DB, Ford DL, Hurt KJ, Bae SS, Suh P, et al. Phospholipase C-γ is required for agonist-induced Ca2+ entry. Cell. 2002;111:529-41. (Stim)
  5. 5. Ma H, Venkatachalam K, Parys JB, Gill DL. Modification of store-operated channel coupling and inositol trisphosphate receptor function by 2-aminoethoxydiphenyl borate in DT40 lymphocytes. J Biol Chem. 2002;277:6915-22. (Stim)
  6. 6. Brummer T, Naegele H, Reth M, Misawa Y. Identification of novel ERK-mediated feedback phosphorylation sites at the C-terminus of B-Raf. Oncogene. 2003;22:8823-34. (Stim)
  7. 7. Boehning D, Patterson RL, Sedaghat L, Glebova NO, Kurosaki T, Snyder SH. Cytochrome c binds to inositol (1,4,5) trisphosphate receptors, amplifying calcium-dependent apoptosis. Nat Cell Biol. 2003;5:1051-61. (Stim, Apop)
  8. 8. Assefa Z, Bultynck G, Szlufcik K, Nadif Kasri N, Vermassen E, Goris J, et al. Caspase-3-induced truncation of type 1 inositol trisphosphate receptor accelerates apoptotic cell death and induces inositol trisphosphate-independent calcium release during apoptosis. J Biol Chem. 2004;279:43227-36. (Stim, Apop)
  9. 9. Morita T, Tanimura A, Nezu A, Kurosaki T, Tojyo Y. Functional analysis of the green fluorescent protein-tagged inositol 1,4,5-trisphosphate receptor type 3 in Ca2+ release and entry in DT40 B lymphocytes. Biochem J. 2004;382:793-801. (Stim)
  10. 10. van Rossum DB, Patterson RL, Kiselyov K, Boehning D, Barrow RK, Gill DL, et al. Agonist-induced Ca2+ entry determined by inositol 1,4,5-trisphosphate recognition. Proc Natl Acad Sci USA. 2004;101:2323-7. (Stim)
  11. 11. Cui J, Matkovich SJ, deSouza N, Li S, Rosemblit N, Marks AR. Regulation of the type 1 inositol 1,4,5-trisphosphate receptor by phosphorylation at tyrosine 353. J Biol Chem. 2004;279:16311-6. (Stim)
  12. 12. Guillemette J, Caron AZ, Regimbald-Dumas Y, Arguin G, Mignery GA, Boulay G, et al. Expression of a truncated form of inositol 1,4,5-trisphosphate receptor type III in the cytosol of DT40 triple inositol 1,4,5-trisphosphate receptor-knockout cells. Cell Calcium. 2005;37:97-104. (Stim)
  13. 13. He L, Hewavitharana T, Soboloff J, Spassova MA, Gill DL. A functional link between store-operated and TRPC channels revealed by the 3,5-bis(trifluoromethyl)pyrazole derivative, BTP2. J Biol Chem. 2005;280:10997-11006. (Stim)
  14. 14. Soulsby MD, Wojcikiewicz RJ. Calcium mobilization via type III inositol 1,4,5-trisphosphate receptors is not altered by PKA-mediated phosphorylation of serines 916, 934, and 1832. Cell Calcium. 2007;42:261-70. (Stim)
  15. 15. Terashima M, Takahashi M, Shimoyama M, Tanigawa Y, Urano T, Tsuchiya M. Glycosylphosphatidylinositol-anchored arginine-specific ADP-ribosyltransferase7.1 (Art7.1) on chicken B cells: the possible role of Art7 in B cell receptor signalling and proliferation. Mol Cell Biochem. 2009;320:93-100. (Stim)
  16. 16. Morita T, Tanimura A, Baba Y, Kurosaki T, Tojyo Y. A Stim1-dependent, noncapacitative Ca2+-entry pathway is activated by B-cell-receptor stimulation and depletion of Ca2+. J Cell Sci. 2009;122:1220-8. (Stim)
  17. 17. Alinikula J, Kohonen P, Nera K, Lassila O. Concerted action of Helios and Ikaros controls the expression of the inositol 5-phosphatase SHIP. Eur J Immunol. 2010;40:2599-607. (Stim, FC)
  18. 18. Nera K, Alinikula J, Terho P, Narvi E, Törnquist K, Kurosaki T, et al. Ikaros has a crucial role in regulation of B cell receptor signaling. Eur J Immunol. 2006;36:516-25. (FC)
  19. 19. Girish CK, Smith TK, Boermans HJ, Karrow NA. Effects of feeding blends of grains naturally contaminated with Fusarium mycotoxins on performance, hematology, metabolism, and immunocompetence of turkeys. Poult Sci. 2008;87:421-32. (FC, Turkey Reactivity)
  20. 20. Del Cacho E, Gallego M, López-Bernard F, Sánchez-Acedo C, Lillehoj HS. Isolation of chicken follicular dendritic cells. J Immunol Methods. 2008;334:59-69. (FC)
  21. 21. Del Cacho E, Gallego M, Lillehoj HS, López-Bernard F, Sánchez-Acedo C. Avian follicular and interdigitating dendritic cells: isolation and morphologic, phenotypic, and functional analyses. Vet Immunol Immunopathol. 2009;129:66-75. (FC)
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