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Mouse Anti-Human IL-21-UNLB (SB134b)

Cat. No.:
15900-01
Purified Anti-Human IL-21 antibody for use in ELISA assays.
$195.00
Size Price (USD) Quantity
0.5 mg $195.00
More Information
Clone SB134b
Isotype Mouse (BALB/c) IgG2bκ
Isotype Control Mouse IgG2b-UNLB (A-1)
Specificity Human IL-21
Alternative Names Interleukin-21, Za11
Description Interleukin-21 (IL-21) is a four helical bundle type I cytokine. The mature form of human IL-21 is a 131 amino acid protein. IL-21 is expressed primarily by NKT and CD4+ T cells, particularly the inflammatory Th17 subset, and has pleiotropic effects on both innate and adaptive immune responses. The effects of IL-21 include promotion of antibody production, NK cell differentiation, proliferation and differentiation of cells of monocyte and granulocyte lineages, costimulation of T cells, and augmentation of antitumor activity of CD8+ T cells. Studies have shown that IL-21 is also an autocrine cytokine that potently induces Th17 differentiation and suppresses Foxp3 expression, and serves as a target for treating inflammatory diseases.
Immunogen E. coli-expressed human IL-21
Conjugate UNLB (Unconjugated)
Buffer Formulation Borate buffered saline, pH 8.2
Clonality Monoclonal
Concentration 0.5 mg/mL
Volume 1.0 mL
Recommended Storage 2-8°C
Applications ELISA – Quality tested

Note – May be paired with the biotinylated clone SB134f (SB Cat. No. 15910-08) in a sandwich ELISA

RRID Number AB_2794989
Gene ID 59067 (Human)
Gene ID Symbol IL21 (Human)
Gene ID Aliases CVID11; IL-21; Za11
UniProt ID Q9HBE4 (Human)
UniProt Name IL21_HUMAN (Human)

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