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Mouse Anti-Human IL-33-UNLB (SB127j)

Cat. No.:
15710-01
Purified Anti-Human IL-33 antibody for use in ELISA assays.
$270.00
Size Price (USD) Quantity
0.5 mg $270.00
More Information
Clone SB127j
Isotype Mouse (BALB/c) IgG2aκ
Isotype Control Mouse IgG2a-UNLB (HOPC-1)
Specificity Human IL-33
Alternative Names Interleukin-33, IL-1F11, NF-HEV
Description Interleukin-33 (IL-33), also known as NF-HEV, is a 30 kDa protein and a member of the IL-1 family. This pro-inflammatory cytokine is produced by a variety of cells but is primarily expressed by endothelial and smooth muscle cells in the vasculature and airways. IL-33 binds to the ST2 receptor on target cells which results in the activation of multiple signaling pathways including NF-κB and MAP kinases. Studies have shown that IL-33 promotes T helper type 2 (Th2) cell-mediated immune responses and upregulates production of Th2 associated cytokines including IL-4, IL-5, and IL-13. In vivo administration of this cytokine in mice results in eosinophilia and splenomegaly as well as induced severe pathological changes in the lungs, gastrointestinal tract, and other mucosal organs.
Immunogen E. coli-expressed human IL-33
Conjugate UNLB (Unconjugated)
Buffer Formulation Borate buffered saline, pH 8.2
Clonality Monoclonal
Concentration 0.5 mg/mL
Volume 1.0 mL
Recommended Storage 2-8°C
Applications ELISA – Quality tested

Note – May be paired with the biotinylated clone SB127c (SB Cat. No. 15700-08) in a sandwich ELISA

RRID Number AB_2794945
Gene ID 90865 (Human)
Gene ID Symbol IL33 (Human)
Gene ID Aliases C9orf26; DVS27; IL1F11; NF-HEV; NFEHEV
UniProt ID O95760 (Human)
UniProt Name IL33_HUMAN (Human)

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