Mouse Anti-Mouse Ly-49I-PE (YLI-90)
Cat. No.:
1802-09
PE Anti-Mouse Ly-49I antibody for use in flow cytometry assays.
$193.00
![C57BL/6 mouse splenocytes were stained with Mouse Anti-Mouse Ly-49I-PE (SB Cat. No. 1802-09) and Mouse Anti-Mouse NK1.1-FITC (SB Cat. No. 1805-02).](https://www.southernbiotech.com/media/catalog/product/cache/7215ceb8c027a94f96b2599083a59844/e/e/ee76e6c0b2b1e57e7d900013c92fb6482e6fbdd64864a8b239a60274457c7334.jpeg)
![C57BL/6 mouse splenocytes were stained with Mouse Anti-Mouse Ly-49I-PE (SB Cat. No. 1802-09) and Mouse Anti-Mouse NK1.1-FITC (SB Cat. No. 1805-02).](https://www.southernbiotech.com/media/catalog/product/cache/bea6149526ccf959e2544cf4e4180429/e/e/ee76e6c0b2b1e57e7d900013c92fb6482e6fbdd64864a8b239a60274457c7334.jpeg)
Clone | YLI-90 |
---|---|
Isotype | Mouse (BALB/c) IgG1κ |
Isotype Control | Mouse IgG1-PE (15H6) |
Specificity | Mouse Ly-49I |
Alternative Names | Ly-49 |
Description | The monoclonal antibody YLI-90 reacts with the B6 allele of Ly49I, a member of the lectin-like homodimeric Ly49 family of cell surface receptors. Mouse Ly49 receptors exhibit allelic specificity for MHC class I Ia molecules and are thought to serve to prevent natural killer (NK) cells from attacking normal cells while allowing them to attack infected or transformed cells in which class I molecules have been down-regulated. These inhibitory receptors are also expressed on subpopulations of mouse CD8+ T cells. The YLI-90 antibody stains ~45% of NK1.1+CD3- splenocytes from C57BL/6 mice. |
Immunogen | CHO-K1 cells transfected with B6 allele of Ly49I gene |
Conjugate | PE (R-phycoerythrin) |
Buffer Formulation | Phosphate buffered saline containing < 0.1% sodium azide and a stabilizer |
Clonality | Monoclonal |
Concentration | 0.1 mg/mL |
Volume | 1.0 mL |
Recommended Storage | 2-8°C; Avoid exposure to light; Do not freeze |
Applications |
Flow Cytometry – Quality tested 1,2 |
RRID Number | AB_2795334 |
Gene ID |
16640 (Mouse) |
Gene ID Symbol |
Klra9 (Mouse) |
Gene ID Aliases | LY49I1; Ly49I |
Documentation
Certificate of Analysis Lookup
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- 1. Coles MC, McMahon CW, Takizawa H, Raulet DH. Memory CD8 T lymphocytes express inhibitory MHC-specific Ly49 receptors. Eur J Immunol. 2000;30:236-44. (Immunogen, FC)
- 2. Corral L, Takizawa H, Hanke T, Jamieson AM, Raulet DH. A new monoclonal antibody reactive with several Ly49 NK cell receptors mediates redirected lysis of target cells. Hybridoma. 1999;18:359-66. (FC)