| Immunogen |
Recombinant N-terminal cytokeratin 18
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| Description |
Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1-8). The two keratin types share only 30% sequence homology. Keratins demonstrate tissue- and differentiation-specific expression profiles. Cytokeratin 18 is a type I intermediate filament protein that exists as a heterotetramer composed of two type I and two type II keratins. Cytokeratin 18 is expressed in all simple type epithelia and basal cells of many squamous and non-epidermal epithelia and is often co-expressed with cytokeratin 8. Tissues from the gastrointestinal tract, respiratory tract, and urogenital tract as well as endocrine and exocrine tissues and mesothelial cells are positive for cytokeratin 18.
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| Buffer Formulation |
Borate buffered saline, pH 8.2
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| Storage & Handling |
2-8°C
Please refer to product specific SDS
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| Applications |
Applications for relevant formats of this clone include - ELISA – Quality tested
FLISA – Quality tested
Immunohistochemistry-Paraffin Sections 1
Immunocytochemistry 1
Flow Cytometry 2
Western Blot 2
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| Recommended Dilutions |
Please refer to product specific Technical Bulletin
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