Mouse Anti-Cytokeratin 18-UNLB
Cat. No.
10085-01
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Size
0.1 mg
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Price (USD)
$185.00
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Clone |
SB38b
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Isotype |
Mouse (BALB/c) IgG2bκ
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Isotype Control |
Mouse IgG2b-UNLB
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Immunogen |
Recombinant N-terminal cytokeratin 18
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Specificity |
Cytokeratin 18
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Alternalte Name(s) |
CK 18, keratin 18
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Description |
Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1-8). The two keratin types share only 30% sequence homology. Keratins demonstrate tissue- and differentiation-specific expression profiles. Cytokeratin 18 is a type I intermediate filament protein that exists as a heterotetramer composed of two type I and two type II keratins. Cytokeratin 18 is expressed in all simple type epithelia and basal cells of many squamous and non-epidermal epithelia and is often co-expressed with cytokeratin 8. Tissues from the gastrointestinal tract, respiratory tract, and urogenital tract as well as endocrine and exocrine tissues and mesothelial cells are positive for cytokeratin 18.
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Format/Conjugate |
UNLB (Unconjugated)
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Buffer Formulation |
Borate buffered saline, pH 8.2
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Concentration |
0.1 mg/mL
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Volume |
1.0 mL
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Storage & Handling |
2-8°C
Please refer to product specific SDS
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Applications |
Applications for relevant formats of this clone include - ELISA – Quality tested FLISA – Quality tested Immunohistochemistry-Paraffin Sections 1 Immunocytochemistry 1 Flow Cytometry 2 Western Blot 2
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Recommended Dilutions |
Please refer to product specific Technical Bulletin
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RRID |
AB_2794113
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Gene ID |
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Gene Symbol |
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Gene Aliases |
CK-18; CYK18; K18
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Uniprot ID |
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Uniprot Name |
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Human pancreatic carcinoma cell line MIA PaCa-2 was stained with Mouse Anti-Cytokeratin 18-UNLB (SB Cat. No. 10085-01) followed by Donkey Anti-Mouse IgG(H+L), Multi-Species SP ads-AF555 (SB Cat. No. 6415-32) and DAPI.
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Human epithelial carcinoma cell line HEp-2 was stained with Mouse Anti-Cytokeratin 18-UNLB (SB Cat. No. 10085-01) followed by Goat Anti-Mouse IgG2b, Human/Bovine/Horse SP ads-FITC (SB Cat. No. 1093-02) and DAPI.
Human pancreatic carcinoma cell line MIA PaCa-2 was stained with Mouse Anti-Cytokeratin 18-UNLB (SB Cat. No. 10085-01) followed by Donkey Anti-Mouse IgG(H+L), Multi-Species SP ads-AF555 (SB Cat. No. 6415-32) and DAPI.
Human epithelial carcinoma cell line HEp-2 was stained with Mouse Anti-Cytokeratin 18-UNLB (SB Cat. No. 10085-01) followed by Goat Anti-Mouse IgG2b, Human/Bovine/Horse SP ads-FITC (SB Cat. No. 1093-02) and DAPI.
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References
1. | SouthernBiotech published data (IHC-PS, ICC) | 2. | SouthernBiotech unpublished data (FC, WB) |
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