Unlabeled Anti-Cytokeratin 18, SB38b

Cat. No.
10085-01

Size
0.1 mg

Price (USD)
$185.00

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Clone	SB38b
Isotype	Mouse (BALB/c) IgG_2bκ
Isotype Control	Mouse IgG_2b-UNLB
Immunogen	Recombinant N-terminal cytokeratin 18
Specificity	Cytokeratin 18
Alternalte Name(s)	CK 18, keratin 18
Description	Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1-8). The two keratin types share only 30% sequence homology. Keratins demonstrate tissue- and differentiation-specific expression profiles. Cytokeratin 18 is a type I intermediate filament protein that exists as a heterotetramer composed of two type I and two type II keratins. Cytokeratin 18 is expressed in all simple type epithelia and basal cells of many squamous and non-epidermal epithelia and is often co-expressed with cytokeratin 8. Tissues from the gastrointestinal tract, respiratory tract, and urogenital tract as well as endocrine and exocrine tissues and mesothelial cells are positive for cytokeratin 18.
Format/Conjugate	UNLB (Unconjugated)
Buffer Formulation	Borate buffered saline, pH 8.2
Concentration	0.1 mg/mL
Volume	1.0 mL
Storage & Handling	2-8°C Please refer to product specific SDS
Applications	Applications for relevant formats of this clone include - ELISA – Quality tested FLISA – Quality tested Immunohistochemistry-Paraffin Sections ¹ Immunocytochemistry ¹ Flow Cytometry ² Western Blot ²
Recommended Dilutions	Please refer to product specific Technical Bulletin
RRID	AB_2794113

Gene ID	3875 (Human)
Gene Symbol	KRT18 (Human)
Gene Aliases	CK-18; CYK18; K18
Uniprot ID	P05783 (Human)
Uniprot Name	K1C18_HUMAN

Human pancreatic carcinoma cell line MIA PaCa-2 was stained with Mouse Anti-Cytokeratin 18-UNLB (SB Cat. No. 10085-01) followed by Donkey Anti-Mouse IgG(H+L), Multi-Species SP ads-AF555 (SB Cat. No. 6415-32) and DAPI.
Human epithelial carcinoma cell line HEp-2 was stained with Mouse Anti-Cytokeratin 18-UNLB (SB Cat. No. 10085-01) followed by Goat Anti-Mouse IgG2b, Human/Bovine/Horse SP ads-FITC (SB Cat. No. 1093-02) and DAPI.

Human pancreatic carcinoma cell line MIA PaCa-2 was stained with Mouse Anti-Cytokeratin 18-UNLB (SB Cat. No. 10085-01) followed by Donkey Anti-Mouse IgG(H+L), Multi-Species SP ads-AF555 (SB Cat. No. 6415-32) and DAPI.

Human epithelial carcinoma cell line HEp-2 was stained with Mouse Anti-Cytokeratin 18-UNLB (SB Cat. No. 10085-01) followed by Goat Anti-Mouse IgG2b, Human/Bovine/Horse SP ads-FITC (SB Cat. No. 1093-02) and DAPI.