Mouse Anti-Cytokeratin 18-UNLB
Cat. No.
10085-01
|
Size
0.1 mg
|
Price (USD)
$185.00
|
| Clone |
SB38b
|
| Isotype |
Mouse (BALB/c) IgG2bκ
|
| Isotype Control |
Mouse IgG2b-UNLB
|
| Immunogen |
Recombinant N-terminal cytokeratin 18
|
| Specificity |
Cytokeratin 18
|
| Alternalte Name(s) |
CK 18, keratin 18
|
| Description |
Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1-8). The two keratin types share only 30% sequence homology. Keratins demonstrate tissue- and differentiation-specific expression profiles. Cytokeratin 18 is a type I intermediate filament protein that exists as a heterotetramer composed of two type I and two type II keratins. Cytokeratin 18 is expressed in all simple type epithelia and basal cells of many squamous and non-epidermal epithelia and is often co-expressed with cytokeratin 8. Tissues from the gastrointestinal tract, respiratory tract, and urogenital tract as well as endocrine and exocrine tissues and mesothelial cells are positive for cytokeratin 18.
|
| Format/Conjugate |
UNLB (Unconjugated)
|
| Buffer Formulation |
Borate buffered saline, pH 8.2
|
| Concentration |
0.1 mg/mL
|
| Volume |
1.0 mL
|
| Storage & Handling |
2-8°C
Please refer to product specific SDS
|
| Applications |
Applications for relevant formats of this clone include - ELISA – Quality tested
FLISA – Quality tested
Immunohistochemistry-Paraffin Sections 1
Immunocytochemistry 1
Flow Cytometry 2
Western Blot 2
|
| Recommended Dilutions |
Please refer to product specific Technical Bulletin
|
| RRID |
AB_2794113
|
| Gene ID |
|
| Gene Symbol |
|
| Gene Aliases |
CK-18; CYK18; K18
|
| Uniprot ID |
|
| Uniprot Name |
|
|
|
-
Human pancreatic carcinoma cell line MIA PaCa-2 was stained with Mouse Anti-Cytokeratin 18-UNLB (SB Cat. No. 10085-01) followed by Donkey Anti-Mouse IgG(H+L), Multi-Species SP ads-AF555 (SB Cat. No. 6415-32) and DAPI.
-
Human epithelial carcinoma cell line HEp-2 was stained with Mouse Anti-Cytokeratin 18-UNLB (SB Cat. No. 10085-01) followed by Goat Anti-Mouse IgG2b, Human/Bovine/Horse SP ads-FITC (SB Cat. No. 1093-02) and DAPI.
Human pancreatic carcinoma cell line MIA PaCa-2 was stained with Mouse Anti-Cytokeratin 18-UNLB (SB Cat. No. 10085-01) followed by Donkey Anti-Mouse IgG(H+L), Multi-Species SP ads-AF555 (SB Cat. No. 6415-32) and DAPI.
Human epithelial carcinoma cell line HEp-2 was stained with Mouse Anti-Cytokeratin 18-UNLB (SB Cat. No. 10085-01) followed by Goat Anti-Mouse IgG2b, Human/Bovine/Horse SP ads-FITC (SB Cat. No. 1093-02) and DAPI.
|
References
| 1. | SouthernBiotech published data (IHC-PS, ICC) | | 2. | SouthernBiotech unpublished data (FC, WB) |
|